5-(4-fluorophenyl)-2-phenyl-3-(4-(trifluoromethyl)phenyl)dihydro-2H-pyrrolo[3,4-d]isoxazole-4,6(5H,6aH)-dione

Base Information

Chemical Name:5-(4-fluorophenyl)-2-phenyl-3-(4-(trifluoromethyl)phenyl)dihydro-2H-pyrrolo[3,4-d]isoxazole-4,6(5H,6aH)-dione
CAS No.:6111-17-7
Molecular Formula:C24H16F4N2O3
Molecular Weight:456.3891
Hs Code.:
DSSTox Substance ID:DTXSID60387309

Synonyms:6111-17-7;473445-12-4;5-(4-fluorophenyl)-2-phenyl-3-(4-(trifluoromethyl)phenyl)dihydro-2H-pyrrolo[3,4-d]isoxazole-4,6(5H,6aH)-dione;3-(4-fluorophenyl)-7-phenyl-6-[4-(trifluoromethyl)phenyl]-8-oxa-3,7-diazabicyclo[3.3.0]octane-2,4-dione;5-(4-fluorophenyl)-2-phenyl-3-[4-(trifluoromethyl)phenyl]-hexahydro-2H-pyrrolo[3,4-d][1,2]oxazole-4,6-dione;5-(4-fluorophenyl)-2-phenyl-3-[4-(trifluoromethyl)phenyl]dihydro-2H-pyrrolo[3,4-d][1,2]oxazole-4,6(3H,5H)-dione;DTXSID60387309;STL020245;AKOS000540209;AKOS016318528;EU-0075592;SR-01000467355;SR-01000467355-1;F1065-0558;5-(4-Fluoro-phenyl)-2-phenyl-3-(4-trifluoromethyl-phenyl)-tetrahydro-pyrrolo[3,4

Suppliers and Price of 5-(4-fluorophenyl)-2-phenyl-3-(4-(trifluoromethyl)phenyl)dihydro-2H-pyrrolo[3,4-d]isoxazole-4,6(5H,6aH)-dione

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 5-(4-fluorophenyl)-2-phenyl-3-(4-(trifluoromethyl)phenyl)dihydro-2H-pyrrolo[3,4-d]isoxazole-4,6(5H,6aH)-dione

Chemical Property:

Vapor Pressure:3.89E-15mmHg at 25°C
Boiling Point:616.6°Cat760mmHg
Flash Point:326.7°C
Density:1.428g/cm³
XLogP3:5
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:8
Rotatable Bond Count:3
Exact Mass:456.10970502
Heavy Atom Count:33
Complexity:741

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)N2C(C3C(O2)C(=O)N(C3=O)C4=CC=C(C=C4)F)C5=CC=C(C=C5)C(F)(F)F

Technology Process of 5-(4-fluorophenyl)-2-phenyl-3-(4-(trifluoromethyl)phenyl)dihydro-2H-pyrrolo[3,4-d]isoxazole-4,6(5H,6aH)-dione

There total 3 articles about 5-(4-fluorophenyl)-2-phenyl-3-(4-(trifluoromethyl)phenyl)dihydro-2H-pyrrolo[3,4-d]isoxazole-4,6(5H,6aH)-dione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 6111-15-5
1,1,1-trichloro-2-methyl-pent-4-en-2-ol

: 6111-17-7
1,1,1-trichloro-2-methyl-pentan-2-ol

Guidance literature:: With hydrogen; platinum(IV) oxide; In ethanol;
DOI:10.1039/j39660000670

Reference yield:

: 67-66-3,8013-54-5
chloroform

: 107-87-9
2-Pentanone

: 6111-17-7
1,1,1-trichloro-2-methyl-pentan-2-ol

Guidance literature:: chloroform; 2-Pentanone; With lithium hexamethyldisilazane; In tetrahydrofuran; at -78 ℃; for 1.5h;

With ammonium chloride; In tetrahydrofuran; water; Saturated solution;
DOI:10.1021/ja207607s