2-Propanesulfonic acid, 2-methyl-, anhydride

Base Information

• Chemical Name: 2-Propanesulfonic acid, 2-methyl-, anhydride
• CAS No.: 75975-45-0
• Molecular Formula: C8H18O5S2
• Molecular Weight: 258.36
• Mol file: 75975-45-0.mol

Synonyms:

Chemical Property of 2-Propanesulfonic acid, 2-methyl-, anhydride

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-Propanesulfonic acid, 2-methyl-, anhydride

There total 1 articles about 2-Propanesulfonic acid, 2-methyl-, anhydride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 15.0%

tert-butylsulfinyl chloride (31562-43-3) + N-hydroxylmethanesulfonamide (50695-55-1) → methanesulfonamide (3144-09-0) + di-tert-butyl thiosulfonate (31562-41-1) + trifluoromethane sulfonic anhydride (75975-45-0) + C5H13NO4S2 (75975-41-6)

Guidance literature:

With pyridine; In acetone; at 20 ℃; for 2h; Mechanism; Product distribution; other N-hydroxy sulfonamides;

DOI:10.1021/jo00318a033

Reference yield: 95.0%

trifluoromethane sulfonic anhydride (75975-45-0) + 5-hydroxy-7-methoxy-2,2-dimethyl-benzo[1,3]dioxin-4-one (532394-23-3) → 7-methoxy-2,2-dimethyl-5-(trifluoromethylsulfonyloxy)benzo[1,3]dioxin-4-one (532394-17-5)

Guidance literature:

With pyridine; at 0 - 20 ℃; Inert atmosphere;

DOI:10.1016/j.tetlet.2011.10.137

Reference yield: 72.0%

trifluoromethane sulfonic anhydride (75975-45-0) + (R)-2-(4-methylenetetrahydro-2H-pyran-2-yl)phenol → (R)-2-(4-methylenetetrahydro-2H-pyran-2-yl)phenyl trifluoromethanesulfonate

Guidance literature:

With pyridine; In dichloromethane; at 20 ℃; for 1h;

DOI:10.1002/anie.201500219

upstream raw materials:

tert-butylsulfinyl chloride

N-hydroxylmethanesulfonamide

Downstream raw materials:

7-methoxy-2,2-dimethyl-5-(trifluoromethylsulfonyloxy)benzo[1,3]dioxin-4-one

Refernces