TrifluoroMethanesulfonic Acid 7-Methoxy-2,2-diMethyl-4-oxo-4H-1,3-benzodioxin-5-yl Ester

Base Information

Chemical Name:TrifluoroMethanesulfonic Acid 7-Methoxy-2,2-diMethyl-4-oxo-4H-1,3-benzodioxin-5-yl Ester
CAS No.:532394-17-5
Molecular Formula:C₁₂H₁₁F₃O₇S
Molecular Weight:356.276
Hs Code.:
Mol file:532394-17-5.mol

Synonyms:7-methoxy-2,2-dimethyl-5-(trifluoromethylsulfonyloxy)benzo[1,3]dioxin-4-one

Suppliers and Price of TrifluoroMethanesulfonic Acid 7-Methoxy-2,2-diMethyl-4-oxo-4H-1,3-benzodioxin-5-yl Ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
7-Methoxy-2,2-dimethyl-4-oxo-4H-1,3-benzodioxin-5-ylTriflate
25mg
$ 165.00

Medical Isotopes, Inc.
TrifluoromethanesulfonicAcid7-Methoxy-2,2-dimethyl-4-oxo-4H-1,3-benzodioxin-5-ylEster
25 mg
$ 650.00

Total 2 raw suppliers

Chemical Property of TrifluoroMethanesulfonic Acid 7-Methoxy-2,2-diMethyl-4-oxo-4H-1,3-benzodioxin-5-yl Ester

Chemical Property:

Melting Point:58-59 °C(Solv: hexane (110-54-3); ethyl acetate (141-78-6))
Boiling Point:481.4±45.0 °C(Predicted)
Density:1.492±0.06 g/cm3(Predicted)
Solubility.:Chloroform, Ethyl Acetate

Purity/Quality:

99% ^*data from raw suppliers

7-Methoxy-2,2-dimethyl-4-oxo-4H-1,3-benzodioxin-5-ylTriflate ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Uses 5-Hydroxy-7-methoxy-2,2-dimethyl-4H-1,3-benzodioxin-4-one is an intermediate for the synthesis of the precursor compound for Altenuene (A575740), a toxin isolated from the fungus Alternaria tenuis.

Technology Process of TrifluoroMethanesulfonic Acid 7-Methoxy-2,2-diMethyl-4-oxo-4H-1,3-benzodioxin-5-yl Ester

There total 7 articles about TrifluoroMethanesulfonic Acid 7-Methoxy-2,2-diMethyl-4-oxo-4H-1,3-benzodioxin-5-yl Ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

: 358-23-6
trifluoromethylsulfonic anhydride

: 532394-23-3
5-hydroxy-7-methoxy-2,2-dimethyl-benzo[1,3]dioxin-4-one

: 532394-17-5
7-methoxy-2,2-dimethyl-5-(trifluoromethylsulfonyloxy)benzo[1,3]dioxin-4-one

Guidance literature:: With pyridine; at 0 ℃; for 1.5h; Inert atmosphere;
DOI:10.1021/jo5024602

Reference yield: 95.0%

: 75975-45-0
trifluoromethane sulfonic anhydride

: 532394-23-3
5-hydroxy-7-methoxy-2,2-dimethyl-benzo[1,3]dioxin-4-one

: 532394-17-5
7-methoxy-2,2-dimethyl-5-(trifluoromethylsulfonyloxy)benzo[1,3]dioxin-4-one

Guidance literature:: With pyridine; at 0 - 20 ℃; Inert atmosphere;
DOI:10.1016/j.tetlet.2011.10.137

Reference yield: 78.0%

: 67-56-1
methanol

: 137571-73-4
5,7-dihydroxy-2,2-dimethyl-4H-benzo[d][1,3]dioxin-4-one

: 532394-17-5
7-methoxy-2,2-dimethyl-5-(trifluoromethylsulfonyloxy)benzo[1,3]dioxin-4-one

Guidance literature:: methanol; 5,7-dihydroxy-2,2-dimethyl-4H-benzo[d][1,3]dioxin-4-one; With triphenylphosphine; diethylazodicarboxylate;

Enzymatic reaction;
DOI:10.1016/j.tetlet.2010.04.024