6,7-Dichloroquinoxalin-2-amine

Base Information

• Chemical Name: 6,7-Dichloroquinoxalin-2-amine
• CAS No.: 76002-68-1
• Molecular Formula: C₈H₅Cl₂N₃
• Molecular Weight: 214.054
• Hs Code.: 2933990090
• DSSTox Substance ID: DTXSID00555328
• Wikidata: Q82436642
• Mol file: 76002-68-1.mol

Synonyms:6,7-Dichloroquinoxalin-2-amine;76002-68-1;6,7-DICHLORO-QUINOXALIN-2-YLAMINE;6,7-dichloroquinoxalin-2-ylamine;SCHEMBL11372767;DTXSID00555328;IEUXCSKRIXCLGL-UHFFFAOYSA-N;2-amino-6,7-dichloro-quinoxaline;AMY21050;BDA00268;CS-0527888

Chemical Property of 6,7-Dichloroquinoxalin-2-amine

Chemical Property:

• PSA: 51.80000
• LogP: 3.10000
• Storage Temp.: 2-8°C
• XLogP3: 2.8
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 0
• Exact Mass: 212.9860526
• Heavy Atom Count: 13
• Complexity: 190

Purity/Quality:

98.5% ^*data from raw suppliers

6,7-Dichloroquinoxalin-2-amine 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=C2C(=CC(=C1Cl)Cl)N=C(C=N2)N

Technology Process of 6,7-Dichloroquinoxalin-2-amine

There total 3 articles about 6,7-Dichloroquinoxalin-2-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 48.0%

7,8-dichloroalloxazine (58590-56-0) → 2-amino-6,7-dichloroquinoxaline (76002-68-1)

Guidance literature:

With sulfuric acid; at 240 ℃; for 0.166667h;

DOI:10.1021/jm00401a009

Reference yield:

4,5-Dichloro-1,2-phenylenediamine (5348-42-5) + 7,8-dichloroalloxazine (58590-56-0) + alloxan monohydrate (2244-11-3) → 2-amino-6,7-dichloroquinoxaline (76002-68-1)

Guidance literature:

With boric acid; In sulfuric acid; acetic acid;

Reference yield:

4,5-Dichloro-1,2-phenylenediamine (5348-42-5) → 2-amino-6,7-dichloroquinoxaline (76002-68-1)

Guidance literature:

Multi-step reaction with 2 steps

1: 85 percent / boric acid / acetic acid / Ambient temperature

2: 48 percent / H₂SO₄ / 0.17 h / 240 °C

With sulfuric acid; boric acid; In acetic acid;

DOI:10.1021/jm00401a009

upstream raw materials:

7,8-dichloroalloxazine

4,5-Dichloro-1,2-phenylenediamine

alloxan monohydrate