Quinoline-3-carboxylic acid

Base Information

Chemical Name:Quinoline-3-carboxylic acid
CAS No.:6480-68-8
Molecular Formula:C10H7NO2
Molecular Weight:173.171
Hs Code.:29334900
European Community (EC) Number:229-337-3
NSC Number:403263
UNII:D98JB7TM7H
DSSTox Substance ID:DTXSID90215101
Nikkaji Number:J225.146I
Wikidata:Q27464678
ChEMBL ID:CHEMBL275098
Mol file:6480-68-8.mol

Synonyms:Quinoline-3-carboxylic acid;6480-68-8;3-Quinolinecarboxylic acid;3-Quinoline carboxylic acid;MFCD00006770;CHEMBL275098;EINECS 229-337-3;NSC-403263;3-carboxyquinoline;Q3C;3,3-Di-indolylmethane;3-quinolylcarboxylic acid;D98JB7TM7H;Oprea1_271938;SCHEMBL28048;DTXSID90215101;3-Quinolinecarboxylic acid, 98%;BCP26872;BBL100196;BDBM50518657;NSC403263;STL553707;AKOS000269791;CS-W007519;DS-0491;FS-2157;NSC 403263;SB67442;AC-12219;SY004162;AM20070150;EU-0033244;FT-0636161;Q0090;EN300-55633;SR-01000596889;J-650260;SR-01000596889-1;W-203408;3-Quinolinecarboxylic acid, purum, >=98.0% (HPLC);Q27464678;F0406-3603;Z838909446

Suppliers and Price of Quinoline-3-carboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
3-Quinolinecarboxylic acid
100g
$ 1550.00

TRC
3-Quinolinecarboxylic acid
50g
$ 1020.00

TCI Chemical
3-Quinolinecarboxylic Acid >98.0%(HPLC)(T)
5g
$ 162.00

TCI Chemical
3-Quinolinecarboxylic Acid >98.0%(HPLC)(T)
1g
$ 48.00

SynQuest Laboratories
Quinoline-3-carboxylic acid 97.0%
25 g
$ 165.00

SynQuest Laboratories
Quinoline-3-carboxylic acid 97.0%
1 g
$ 22.00

SynQuest Laboratories
Quinoline-3-carboxylic acid 97.0%
5 g
$ 40.00

Sigma-Aldrich
3-Quinolinecarboxylic acid 98%
1g
$ 52.90

Sigma-Aldrich
3-Quinolinecarboxylic acid 98%
5g
$ 71.80

Sigma-Aldrich
3-Quinolinecarboxylic acid 98%
25g
$ 160.00

Total 79 raw suppliers

Chemical Property of Quinoline-3-carboxylic acid

Chemical Property:

Appearance/Colour:Slightly beige powder.
Vapor Pressure:1.85E-05mmHg at 25°C
Melting Point:277-280 °C(lit.)
Refractive Index:1.5200 (estimate)
Boiling Point:348.7 °C at 760 mmHg
PKA:2.20±0.30(Predicted)
Flash Point:164.7 °C
PSA：50.19000
Density:1.339 g/cm³
LogP:1.93300
Storage Temp.:Refrigerator
Solubility.:DMSO (Slightly), Methanol (Slightly)
XLogP3:1.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:173.047678466
Heavy Atom Count:13
Complexity:205

Purity/Quality:

99%, ^*data from raw suppliers

3-Quinolinecarboxylic acid ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi
Hazard Codes:Xi
Statements: 36/37/38-36/38
Safety Statements: 22-24/25-37/39-26-37

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

Canonical SMILES:C1=CC=C2C(=C1)C=C(C=N2)C(=O)O
Uses A quinoline derivative with antimicrobial activity.

Technology Process of Quinoline-3-carboxylic acid

There total 20 articles about Quinoline-3-carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: 5332-24-1
3-bromoquinoline

: 124-38-9,18923-20-1
carbon dioxide

: 6480-68-8
quinoline-3-carboxylic acid

Guidance literature:: carbon dioxide; With o-phenylenebis(diphenylphosphine); copper(II) acetate monohydrate; In 1,4-dioxane; at 60 ℃; for 0.416667h; Schlenk technique;

3-bromoquinoline; With palladium diacetate; triethylamine; 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene; In 1,4-dioxane; toluene; at 100 ℃; for 7h; Schlenk technique;

Reference yield: 90.0%

: 13669-42-6
3-quinolylcarboxaldehyde

: 6480-68-8
quinoline-3-carboxylic acid

Guidance literature:: With urea-hydrogen peroxide; In formic acid; at 20 ℃; for 2h;
DOI:10.1081/SCC-100104472

Reference yield: 87.0%

: 120277-70-5
3-(bromomethyl)quinoline

: 6480-68-8
quinoline-3-carboxylic acid

Guidance literature:: With 5,10,15,20-tetra(4-nitrophenyl) porphyrinato iron chloride; [bis(acetoxy)iodo]benzene; water; In methanol; at 50 ℃; for 15h;
DOI:10.1016/j.bmcl.2010.07.071