2-[(2-Fluorophenyl)methyl]-1,3-propanediol

Base Information

Chemical Name:2-[(2-Fluorophenyl)methyl]-1,3-propanediol
CAS No.:76727-25-8
Molecular Formula:C10H13FO2
Molecular Weight:184.21
Hs Code.:
DSSTox Substance ID:DTXSID101268341

Synonyms:2-[(2-Fluorophenyl)methyl]-1,3-propanediol;76727-25-8;DTXSID101268341;AKOS017514487

Suppliers and Price of 2-[(2-Fluorophenyl)methyl]-1,3-propanediol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Total 0 raw suppliers

Chemical Property of 2-[(2-Fluorophenyl)methyl]-1,3-propanediol

Chemical Property:

XLogP3:1.2
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:4
Exact Mass:184.08995782
Heavy Atom Count:13
Complexity:137

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C(=C1)CC(CO)CO)F

Technology Process of 2-[(2-Fluorophenyl)methyl]-1,3-propanediol

There total 2 articles about 2-[(2-Fluorophenyl)methyl]-1,3-propanediol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 42.0%

: 59223-72-2
diethyl 2-(2-fluorophenyl)ethane-1,1-dicarboxylate

: 76727-25-8
2-(2-fluorophenylmethyl)propane-1,3-diol

Guidance literature:: With lithium aluminium tetrahydride; In diethyl ether;

Reference yield:

: 446-48-0
o-fluorobenzyl bromide

: 76727-25-8
2-(2-fluorophenylmethyl)propane-1,3-diol

Guidance literature:: Multi-step reaction with 2 steps

1: 62 percent / sodium ethoxide / ethanol / Heating

2: 42 percent / lithium aluminium hydride / diethyl ether

With lithium aluminium tetrahydride; sodium ethanolate; In diethyl ether; ethanol;