Benzoic acid, 2-mercapto-3-methyl-

Base Information

• Chemical Name: Benzoic acid, 2-mercapto-3-methyl-
• CAS No.: 77149-11-2
• Molecular Formula: C8H8O2S
• Molecular Weight: 168.216
• Mol file: 77149-11-2.mol

Synonyms:3-methyl-2-mercaptobenzoic acid;2-Mercapto-3-methylbenzoic acid;2-mercapto-3-benzoic acid;3-methylthiosalicylic acid;Benzoic acid,2-mercapto-3-methyl;

Chemical Property of Benzoic acid, 2-mercapto-3-methyl-

Chemical Property:

• PSA: 76.10000
• LogP: 1.98190

Purity/Quality:

98%min ^*data from raw suppliers

3-methyl-2-sulfanylbenzoicacid ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Benzoic acid, 2-mercapto-3-methyl-

There total 7 articles about Benzoic acid, 2-mercapto-3-methyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 65.0%

3-methylantranilic acid (4389-45-1) + potassium ethyl xanthogenate (140-89-6) → 3-methyl-2-mercaptobenzoic acid (77149-11-2)

Guidance literature:

3-methylantranilic acid; With hydrogenchloride; sodium hydroxide; sodium nitrite; In water; Cooling with ice;

potassium ethyl xanthogenate; In water; at 80 ℃;

With hydrogenchloride; In water; at 20 ℃;

Reference yield:

3-methylantranilic acid (4389-45-1) → 3-methyl-2-mercaptobenzoic acid (77149-11-2)

Guidance literature:

Yield given. Multistep reaction;

DOI:10.1039/P19820001637

Reference yield:

3-methylantranilic acid (4389-45-1) + sodium carbonate (497-19-8) → 3-methyl-2-mercaptobenzoic acid (77149-11-2)

Guidance literature:

With hydrogenchloride; sodium hydroxide; sodium sulfide nonahydrate; hydrogen sulfide; sodium nitrite; In water; acetic acid;

upstream raw materials:

2,2'-dithiobis<3-methylbenzoic acid>

2-<(ethoxythioxomethyl)thio>-3-methylbenzoic acid

3-methylantranilic acid

methyl 2-N,N-dimethylthiocarbamoyloxy-3-methylbenzoate

Downstream raw materials:

2-(acetylthio)-3-methylbenzoic acid

2,2'-dithiobis<3-methylbenzoyl chloride>

2,2'-dithiobis<3-methylbenzoic acid>

Refernces

• 1、 -. "HETEROCYCLIC DERIVATIVE HAVING INHIBITORY ACTIVITY ON TYPE-I 11 -HYDROXYSTEROID DEHYDROGENASE". Page/Page column 46. . Retrieved 2010/08/07.
• 2、 Liepa, Andris J.,Nguyen, Oanh,Saubern, Simon. "Synthesis of some 4-oxothiochromenes and related compounds". . p. 864 - 869. Retrieved 2007/10/03.