Chemical Property of Actarit
Chemical Property:
- Appearance/Colour:crystalline solid
- Vapor Pressure:7.52E-09mmHg at 25°C
- Melting Point:173-175 °C
- Refractive Index:1.604
- Boiling Point:449.1 °C at 760 mmHg
- PKA:4.34±0.10(Predicted)
- Flash Point:225.4 °C
- PSA:66.40000
- Density:1.288 g/cm3
- LogP:1.34510
- Storage Temp.:-20°C
- Solubility.:DMSO, Ethanol, Methanol
- XLogP3:0.8
- Hydrogen Bond Donor Count:2
- Hydrogen Bond Acceptor Count:3
- Rotatable Bond Count:3
- Exact Mass:193.07389321
- Heavy Atom Count:14
- Complexity:219
- Purity/Quality:
-
99% *data from raw suppliers
Actarit *data from reagent suppliers
Safty Information:
- Pictogram(s):
C
- Hazard Codes:C
- Safety Statements:
24/25
- MSDS Files:
-
SDS file from LookChem
Useful:
- Canonical SMILES:CC(=O)NC1=CC=C(C=C1)CC(=O)O
-
Description
Actarit is an orally administered disease-modifying antirheumatic drug launched in
Japan. Although its structure resembles that of non-steroidal anti-inflammatory
drugs, it has no effect on experimental acute inflammation and has no analgesic or
antipyretic effects. Its preventative and therapeutic effects on adjuvant arthritis are
mediated via modulation of production and serum level of interleukin-2 which
enhances production of suppressor T-cells to the immune system, thereby,
preventing development of articular lesions.
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Uses
Antiarthritic Chronic rheumatoid arthritis