1-Oxaspiro[4.5]dec-3-en-2-one, 4-(phenylthio)-

Base Information

Chemical Name:1-Oxaspiro[4.5]dec-3-en-2-one, 4-(phenylthio)-
CAS No.:77199-33-8
Molecular Formula:C15H16O2S
Molecular Weight:260.357
Hs Code.:
DSSTox Substance ID:DTXSID50445806
Nikkaji Number:J861.605A
Wikidata:Q82264334

Synonyms:77199-33-8;1-Oxaspiro[4.5]dec-3-en-2-one, 4-(phenylthio)-;DTXSID50445806;4-(Phenylthio)-1-oxaspiro[4.5]dec-3-en-2-one;3-(Phenylthio)spiro[furan-2(5H),1'-cyclohexan]-5-one

Suppliers and Price of 1-Oxaspiro[4.5]dec-3-en-2-one, 4-(phenylthio)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 1 raw suppliers

Chemical Property of 1-Oxaspiro[4.5]dec-3-en-2-one, 4-(phenylthio)-

Chemical Property:

XLogP3:3.6
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:260.08710092
Heavy Atom Count:18
Complexity:350

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1CCC2(CC1)C(=CC(=O)O2)SC3=CC=CC=C3

Technology Process of 1-Oxaspiro[4.5]dec-3-en-2-one, 4-(phenylthio)-

There total 3 articles about 1-Oxaspiro[4.5]dec-3-en-2-one, 4-(phenylthio)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

: 201230-82-2
carbon monoxide

: 78-27-3
1-Ethynylcyclohexan-1-ol

: 108-98-5
thiophenol

: 77199-33-8
4-Phenylsulfanyl-1-oxa-spiro[4.5]dec-3-en-2-one

: 3-Cyclohexylidene-thiopropionic acid S-phenyl ester

Guidance literature:: tetrakis(triphenylphosphine) palladium⁽⁰⁾; In 1,2-dimethoxyethane; at 100 ℃; under 20685.9 Torr; Yields of byproduct given;
DOI:10.1021/jo970126n

Reference yield: 13.0%

: 201230-82-2
carbon monoxide

: 78-27-3
1-Ethynylcyclohexan-1-ol

: 108-98-5
thiophenol

: 77199-33-8
4-Phenylsulfanyl-1-oxa-spiro[4.5]dec-3-en-2-one

: 3-Cyclohexylidene-thiopropionic acid S-phenyl ester

: 2-cyclohexylidenedithiosuccinic acid di-S-phenyl ester

Guidance literature:: With toluene-4-sulfonic acid; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In tetrahydrofuran; at 100 ℃; under 20685.9 Torr;
DOI:10.1021/jo970126n

Reference yield:

: 706-02-5,63413-91-2
(2E)-3-(phenylthio)acrylic acid

: 108-94-1,11119-77-0,9003-41-2,9075-99-4
cyclohexanone

: 77199-33-8
4-Phenylsulfanyl-1-oxa-spiro[4.5]dec-3-en-2-one

Guidance literature:: With lithium diisopropyl amide; Yield given. Multistep reaction; 1.) THF, -80 deg C, 2.) from -80 deg C to -40 deg C, 3 h;