1,3-Dihydro-5-phenyl-1-(4-piperidinyl)-2H-1,4-benzodiazepin-2-one

Base Information

Chemical Name:1,3-Dihydro-5-phenyl-1-(4-piperidinyl)-2H-1,4-benzodiazepin-2-one
CAS No.:93591-97-0
Molecular Formula:C₂₀H₂₁N₃O
Molecular Weight:319.406
Hs Code.:
ChEMBL ID:CHEMBL161810
DSSTox Substance ID:DTXSID10918304

Synonyms:1,3-Dihydro-5-phenyl-1-(4-piperidinyl)-2H-1,4-benzodiazepin-2-one;93591-97-0;2H-1,4-Benzodiazepin-2-one, 1,3-dihydro-5-phenyl-1-(4-piperidinyl)-;CHEMBL161810;SCHEMBL10372749;DTXSID10918304;QIJMFWQPPHVNGE-UHFFFAOYSA-N;5-Phenyl-1-(piperidin-4-yl)-1,3-dihydro-2H-1,4-benzodiazepin-2-one

Suppliers and Price of 1,3-Dihydro-5-phenyl-1-(4-piperidinyl)-2H-1,4-benzodiazepin-2-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 1 raw suppliers

Chemical Property of 1,3-Dihydro-5-phenyl-1-(4-piperidinyl)-2H-1,4-benzodiazepin-2-one

Chemical Property:

XLogP3:2.5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:319.168462302
Heavy Atom Count:24
Complexity:477

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CNCCC1N2C(=O)CN=C(C3=CC=CC=C32)C4=CC=CC=C4

Technology Process of 1,3-Dihydro-5-phenyl-1-(4-piperidinyl)-2H-1,4-benzodiazepin-2-one

There total 14 articles about 1,3-Dihydro-5-phenyl-1-(4-piperidinyl)-2H-1,4-benzodiazepin-2-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 75-18-3
dimethylsulfide

: 93592-17-7
1,3-dihydro-1-(1-ethoxycarbonyl-4-piperidinyl)-5-phenyl-2H-1,4-benzodiazepin-2-one

: 93591-97-0
1,3-dihydro-1-(4-piperidinyl)-5-phenyl-2H-1,4-benzodiazepin-2-one

Guidance literature:: With methanesulfonic acid;

Reference yield: 86.0%

: 93592-17-7
1,3-dihydro-1-(1-ethoxycarbonyl-4-piperidinyl)-5-phenyl-2H-1,4-benzodiazepin-2-one

: 93591-97-0
1,3-dihydro-1-(4-piperidinyl)-5-phenyl-2H-1,4-benzodiazepin-2-one

Guidance literature:: With methanesulfonic acid; hydrogen bromide; In thiophene; methanol;

Reference yield:

: 93592-30-4
4-(2-Oxo-5-phenyl-2,3-dihydro-benzo[e][1,4]diazepin-1-yl)-piperidine-1-carboxylic acid benzyl ester

: 93591-97-0
1,3-dihydro-1-(4-piperidinyl)-5-phenyl-2H-1,4-benzodiazepin-2-one

Guidance literature:: With aluminium trichloride; methoxybenzene; In nitromethane; dichloromethane; for 20h; Ambient temperature;
DOI:10.1021/jm00383a003