[12]-Gingerol

Base Information

Chemical Name:[12]-Gingerol
CAS No.:77333-95-0
Deprecated CAS:107257-19-2
Molecular Formula:C23H38O4
Molecular Weight:378.552
Hs Code.:
DSSTox Substance ID:DTXSID60873732
Wikidata:Q81981220
Metabolomics Workbench ID:47318

Synonyms:[12]-Gingerol;5-hydroxy-1-(4-hydroxy-3-methoxyphenyl)hexadecan-3-one;(+/-)-[12]-Gingerol;DTXSID60873732;CHEBI:169737;5-Hydroxy-1-(4-hydroxy-3-methoxyphenyl)-3-hexadecanone, 9CI;77333-95-0

Suppliers and Price of [12]-Gingerol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 0 raw suppliers

Chemical Property of [12]-Gingerol

Chemical Property:

XLogP3:6.4
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:16
Exact Mass:378.27700969
Heavy Atom Count:27
Complexity:371

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CCCCCCCCCCCC(CC(=O)CCC1=CC(=C(C=C1)O)OC)O

Technology Process of [12]-Gingerol

There total 13 articles about [12]-Gingerol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 76.0%

: 91815-23-5
4-{2-[2-(2-Hydroxy-tridecyl)-[1,3]dioxolan-2-yl]-ethyl}-2-methoxy-phenol

: 77333-95-0
5-hydroxy-1-(4'-hydroxy-3'-methoxyphenyl)hexadecan-3-one

Guidance literature:: With hydrogen fluoride; In water; acetonitrile; for 0.5h; Ambient temperature;

Reference yield: 64.0%

: (E)-5-hydroxy-1-(4'-hydroxy-3'-methoxyphenyl)-1-hexadecen-3-one

: 77333-95-0
5-hydroxy-1-(4'-hydroxy-3'-methoxyphenyl)hexadecan-3-one

Guidance literature:: With palladium 10% on activated carbon; hydrogen; In ethyl acetate; at 20 ℃; for 4h;
DOI:10.1016/j.foodchem.2014.05.077

Reference yield:

: 1135-24-6,537-98-4
(E)-3-(4-hydroxy-3-methoxyphenyl)acrylic acid

: 77333-95-0
5-hydroxy-1-(4'-hydroxy-3'-methoxyphenyl)hexadecan-3-one

Guidance literature:: Multi-step reaction with 6 steps

1: hydrogen / 5percent palladium on carbon / methanol

2: 78 percent / diethyl phosphorocyanidate, triethylamine / dimethylformamide

3: 89 percent / p-toluenesulfonic acid / benzene / Heating

4: 76 percent / diisobutylaluminum hydride / diethyl ether / 1 h / -20 °C

5: 73 percent / tetrahydrofuran / 1.) -15 deg C, 1 h, 2.) room temperature, 2 h

6: 76 percent / 46percent hydrogen fluoride / H₂O; acetonitrile / 0.5 h / Ambient temperature

With diethyl cyanophosphonate; hydrogen fluoride; hydrogen; diisobutylaluminium hydride; toluene-4-sulfonic acid; triethylamine; palladium on activated charcoal; In tetrahydrofuran; methanol; diethyl ether; water; N,N-dimethyl-formamide; acetonitrile; benzene;