Cyclododecanone, 2-[10-[2-(acetyloxy)-3,4-dimethoxy-6-methylphenyl]-1-oxodecyl]-

Base Information

• Chemical Name: Cyclododecanone, 2-[10-[2-(acetyloxy)-3,4-dimethoxy-6-methylphenyl]-1-oxodecyl]-
• CAS No.: 77711-98-9
• Molecular Formula: C33H52O6
• Molecular Weight: 544.772
• Mol file: 77711-98-9.mol

Synonyms:

Chemical Property of Cyclododecanone, 2-[10-[2-(acetyloxy)-3,4-dimethoxy-6-methylphenyl]-1-oxodecyl]-

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Cyclododecanone, 2-[10-[2-(acetyloxy)-3,4-dimethoxy-6-methylphenyl]-1-oxodecyl]-

There total 3 articles about Cyclododecanone, 2-[10-[2-(acetyloxy)-3,4-dimethoxy-6-methylphenyl]-1-oxodecyl]- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

10-(2'-hydroxy-3',4'-dimethoxy-6'-methylphenyl)decanoic acid (58185-85-6) → 2-<10-(2-acetoxy-3,4-dimethoxy-6-methylphenyl)decanoyl>cyclododecanone (77711-98-9)

Guidance literature:

Multi-step reaction with 3 steps

1: 95.6 percent / conc. H₂SO₄ / 1.5 h / Ambient temperature

2: 91.8 percent / (COCl)2 / benzene / 1 h / 50 °C

3: 1) Et₃N, 2) 6M aq. HCl / 1) CHCl₃, room temperature, 15 h, 2) CHCl₃, reflux, 5h

With hydrogenchloride; oxalyl dichloride; sulfuric acid; triethylamine; In benzene;

DOI:10.1246/bcsj.57.3182

Reference yield:

10-(2-acetoxy-3,4-dimethoxy-6-methylphenyl)decanoic acid (77712-12-0) → 2-<10-(2-acetoxy-3,4-dimethoxy-6-methylphenyl)decanoyl>cyclododecanone (77711-98-9)

Guidance literature:

Multi-step reaction with 2 steps

1: 91.8 percent / (COCl)2 / benzene / 1 h / 50 °C

2: 1) Et₃N, 2) 6M aq. HCl / 1) CHCl₃, room temperature, 15 h, 2) CHCl₃, reflux, 5h

With hydrogenchloride; oxalyl dichloride; triethylamine; In benzene;

DOI:10.1246/bcsj.57.3182

Reference yield:

1-morpholinocyclododecene (101471-80-1) + 10-(2-acetoxy-3,4-dimethoxy-6-methylphenyl)decanoyl chloride (77711-97-8) → 2-<10-(2-acetoxy-3,4-dimethoxy-6-methylphenyl)decanoyl>cyclododecanone (77711-98-9)

Guidance literature:

With hydrogenchloride; triethylamine; Yield given. Multistep reaction; 1) CHCl₃, room temperature, 15 h, 2) CHCl₃, reflux, 5h;

DOI:10.1246/bcsj.57.3182

upstream raw materials:

1-morpholinocyclododecene

10-(2-acetoxy-3,4-dimethoxy-6-methylphenyl)decanoyl chloride

10-(2'-hydroxy-3',4'-dimethoxy-6'-methylphenyl)decanoic acid

10-(2-acetoxy-3,4-dimethoxy-6-methylphenyl)decanoic acid

Downstream raw materials:

22-(3,4-dimethoxy-2-hydroxy-6-methylphenyl)-13-oxodocosanoic acid

22-(3,4-dimethoxy-2-hydroxy-6-methylphenyl)docosanoic acid

6-(21-carbonylhenicosyl)-2,3-dimethoxy-5-methyl-1,4-benzoquinone

22-(2-acetoxy-3,4-dimethoxy-6-methylphenyl)docosanoyl chloride