58185-85-6Relevant articles and documents
Reduction of carboxylic esters
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, (2008/06/13)
A method for producing a compound of the formula: STR1 [wherein R1 and R2 each stand for a lower alkyl group; n denotes an integer of 0 to 21; X stands for hydrogen atom or an optionally protected hydroxyl group; and Y stands for an optionally protected hydroxyl group], which comprises reducing an ester compound of the formula: STR2 [wherein R1, R2, n, X and Y are of the same meaning as defined above, and R3 stands for a lower alkyl group ] with a mixture of sodium borohydride and aluminum chloride. This method give the desired compound in a high yield, and is advantageous from the industrial point of view.
Aralkyl carboxylic acid compounds
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, (2008/06/13)
Novel compounds of the formulae STR1 wherein R represents lower alkyl or lower alkoxy, A represents --CH2 --, --CO-- or STR2 n represents an integer of 1 to 8, X represents hydrogen or hydroxyl which may be protected and Y represents hydroxyl which may be protected, and their esters show an excellent action on the lysosomal membranes of cells, and exhibit excellent pharmacological activities such as physiologic host defense control activity, especially immuno-potentiating activity.