4-Amino-N-[4-(4-methoxyphenyl)-1,3-thiazol-2-yl]benzene-1-sulfonamide

Base Information

Chemical Name:4-Amino-N-[4-(4-methoxyphenyl)-1,3-thiazol-2-yl]benzene-1-sulfonamide
CAS No.:77925-50-9
Molecular Formula:C₁₆H₁₅N₃O₃S₂
Molecular Weight:361.445
Hs Code.:
DSSTox Substance ID:DTXSID90529290
Wikidata:Q82399634

Synonyms:Oprea1_863451;77925-50-9;DTXSID90529290;4-Amino-N-[4-(4-methoxyphenyl)-1,3-thiazol-2-yl]benzene-1-sulfonamide

Suppliers and Price of 4-Amino-N-[4-(4-methoxyphenyl)-1,3-thiazol-2-yl]benzene-1-sulfonamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 4-Amino-N-[4-(4-methoxyphenyl)-1,3-thiazol-2-yl]benzene-1-sulfonamide

Chemical Property:

XLogP3:2.8
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:5
Exact Mass:361.05548370
Heavy Atom Count:24
Complexity:495

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=CC=C(C=C1)C2=CSC(=N2)NS(=O)(=O)C3=CC=C(C=C3)N

Technology Process of 4-Amino-N-[4-(4-methoxyphenyl)-1,3-thiazol-2-yl]benzene-1-sulfonamide

There total 3 articles about 4-Amino-N-[4-(4-methoxyphenyl)-1,3-thiazol-2-yl]benzene-1-sulfonamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 53.0%

: 77925-47-4
N-acetyl-sulfanilic acid-[4-(4-methoxy-phenyl)-thiazol-2-ylamide]

: 77925-50-9
sulfanilic acid-[4-(4-methoxy-phenyl)-thiazol-2-ylamide]

Guidance literature:: With sodium hydroxide; for 1h; Heating;
DOI:10.1080/00021369.1981.10864637

Reference yield:

: 2104-04-3
4-(4-methoxyphenyl)-1,3-thiazol-2-amine

: 77925-50-9
sulfanilic acid-[4-(4-methoxy-phenyl)-thiazol-2-ylamide]

Guidance literature:: Multi-step reaction with 2 steps

1: 70 percent / pyridine / 1 h / Heating

2: 53 percent / 10percent NaOH / 1 h / Heating

With pyridine; sodium hydroxide;
DOI:10.1080/00021369.1981.10864637

Reference yield:

: 121-60-8
p-acetylaminobenzenesulfonyl chloride

: 77925-50-9
sulfanilic acid-[4-(4-methoxy-phenyl)-thiazol-2-ylamide]

Guidance literature:: Multi-step reaction with 2 steps

1: 70 percent / pyridine / 1 h / Heating

2: 53 percent / 10percent NaOH / 1 h / Heating

With pyridine; sodium hydroxide;
DOI:10.1080/00021369.1981.10864637