1-[(4-Chlorophenyl)sulfonyl]-2-pyrrolidinecarboxylic acid

Base Information

Chemical Name:1-[(4-Chlorophenyl)sulfonyl]-2-pyrrolidinecarboxylic acid
CAS No.:73096-27-2
Molecular Formula:C11H12 Cl N O4 S
Molecular Weight:289.74
Hs Code.:2935009090
DSSTox Substance ID:DTXSID70377539
ChEMBL ID:CHEMBL1570041
Mol file:73096-27-2.mol

Synonyms:73096-27-2;1-[(4-chlorophenyl)sulfonyl]-2-pyrrolidinecarboxylic acid;1-(4-chlorophenyl)sulfonylpyrrolidine-2-carboxylic acid;1-(4-Chloro-benzenesulfonyl)-pyrrolidine-2-carboxylic acid;251096-94-3;1-[(4-chlorophenyl)sulfonyl]proline;1-(4-chlorobenzenesulfonyl)pyrrolidine-2-carboxylic acid;1-((4-Chlorophenyl)sulfonyl)pyrrolidine-2-carboxylic acid;1-(4-chlorophenylsulfonyl)pyrrolidine-2-carboxylic acid;1-[(4-chlorophenyl)sulfonyl]pyrrolidine-2-carboxylic acid;proline, 1-[(4-chlorophenyl)sulfonyl]-;Cambridge id 5209106;Oprea1_809935;Oprea1_873364;CBDivE_010036;MLS001166449;SCHEMBL2704403;CHEMBL1570041;DTXSID70377539;HMS1607E18;HMS2877F10;MFCD00172806;STK663587;AKOS000264448;AKOS016039029;1-(4-Chlorobenzene-1-sulfonyl)proline;CCG-103230;10G-428S;SMR000549517;EU-0066860;FT-0641444;SR-01000390034;SR-01000390034-1;Z45681489;1-((4-Chlorophenyl)sulfonyl)pyrrolidine-2-carboxylicacid

Suppliers and Price of 1-[(4-Chlorophenyl)sulfonyl]-2-pyrrolidinecarboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
1-((4-Chlorophenyl)sulfonyl)pyrrolidine-2-carboxylicacid 95+%
5g
$ 553.00

Biosynth Carbosynth
1-[(4-Chlorophenyl)sulfonyl]proline
5 g
$ 578.00

Biosynth Carbosynth
1-[(4-Chlorophenyl)sulfonyl]proline
1 g
$ 170.00

Biosynth Carbosynth
1-[(4-Chlorophenyl)sulfonyl]proline
500 mg
$ 100.00

Biosynth Carbosynth
1-[(4-Chlorophenyl)sulfonyl]proline
250 mg
$ 57.50

Biosynth Carbosynth
1-[(4-Chlorophenyl)sulfonyl]proline
2 g
$ 289.00

American Custom Chemicals Corporation
1-[(4-CHLOROPHENYL)SULFONYL]-2-PYRROLIDINECARBOXYLIC ACID 95.00%
10G
$ 1585.35

American Custom Chemicals Corporation
1-[(4-CHLOROPHENYL)SULFONYL]-2-PYRROLIDINECARBOXYLIC ACID 95.00%
1G
$ 722.80

American Custom Chemicals Corporation
1-[(4-CHLOROPHENYL)SULFONYL]-2-PYRROLIDINECARBOXYLIC ACID 95.00%
500MG
$ 242.55

Alichem
1-((4-Chlorophenyl)sulfonyl)pyrrolidine-2-carboxylicacid
5g
$ 569.16

Total 9 raw suppliers

Chemical Property of 1-[(4-Chlorophenyl)sulfonyl]-2-pyrrolidinecarboxylic acid

Chemical Property:

Vapor Pressure:3.62E-10mmHg at 25°C
Melting Point:102-105°C
Boiling Point:483.7°C at 760 mmHg
PKA:3.34±0.20(Predicted)
Flash Point:246.3°C
PSA：83.06000
Density:1.515±0.06 g/cm3(Predicted)
LogP:2.59640
XLogP3:1.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:3
Exact Mass:289.0175567
Heavy Atom Count:18
Complexity:411

Purity/Quality:

98%,99%, ^*data from raw suppliers

1-((4-Chlorophenyl)sulfonyl)pyrrolidine-2-carboxylicacid 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:Xi

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CC(N(C1)S(=O)(=O)C2=CC=C(C=C2)Cl)C(=O)O

Technology Process of 1-[(4-Chlorophenyl)sulfonyl]-2-pyrrolidinecarboxylic acid

There total 6 articles about 1-[(4-Chlorophenyl)sulfonyl]-2-pyrrolidinecarboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 50.0%

: 98-60-2
4-chlorobenzenesulfonyl chloride

: 147-85-3,25191-13-3,37159-97-0,4305-67-3,4607-28-7
L-proline

: 73096-27-2,251096-94-3
N-(4-chlorophenylsulfonyl)-(S)-proline

Guidance literature:: With potassium carbonate; In tetrahydrofuran; water; at 50 ℃; for 3h;
DOI:10.1002/jps.2600760213

Reference yield:

: 147-85-3,25191-13-3,37159-97-0,4305-67-3,4607-28-7
L-proline

: 98-60-2
4-chlorobenzenesulfonyl chloride

: 73096-27-2,251096-94-3
1-(4-Chloro-benzenesulfonyl)-pyrrolidine-2-carboxylic acid

Guidance literature:: With potassium carbonate; In tetrahydrofuran; at 50 ℃; for 3h;
DOI:10.1021/ac00270a022

Reference yield:

: 1-Allyl-9-[(S)-1-(4-chloro-benzenesulfonyl)-pyrrolidine-2-carbonyl]-1,9-dihydro-β-carboline-2-carboxylic acid 2,2,2-trichloro-ethyl ester

: 73096-27-2,251096-94-3
N-(4-chlorophenylsulfonyl)-(S)-proline

: 316789-86-3
(S)-1-allyl-1,2-dihydro-2-(2,2,2-trichloroethoxycarbonyl)-β-carboline

: 255053-88-4
1-allyl-1,2-dihydro-2-(2,2,2-trichloroethoxycarbonyl)-β-carboline

Guidance literature:: With sodium hydroxide; In tetrahydrofuran; at 20 ℃; for 0.5h; Title compound not separated from byproducts;
DOI:10.1016/S0040-4020(01)00684-6