(trans-2-(Trifluoromethyl)cyclopropyl)methanol

Base Information

Chemical Name:(trans-2-(Trifluoromethyl)cyclopropyl)methanol
CAS No.:78376-92-8
Molecular Formula:C₅H₇F₃O
Molecular Weight:140.105
Hs Code.:2906199090
European Community (EC) Number:832-281-8
Mol file:78376-92-8.mol

Synonyms:(trans-2-(Trifluoromethyl)cyclopropyl)methanol;78376-92-8;[trans-2-(trifluoromethyl)cyclopropyl]methanol;Rac-[(1r,2r)-2-(trifluoromethyl)cyclopropyl]methanol;TRANS-(2-(TRIFLUOROMETHYL)CYCLOPROPYL)METHANOL;((1R,2R)-2-(Trifluoromethyl)cyclopropyl)methanol;[(1R,2R)-2-(trifluoromethyl)cyclopropyl]methanol;(+/-)-(2-trans-(trifluoromethyl)cyclopropyl)methanol;starbld0002765;YZAYHNYHJCPNAR-IUYQGCFVSA-N;MFCD22421752;AKOS016015492;AT22530;CS-0242263;EN300-246605;1688678-84-3

Suppliers and Price of (trans-2-(Trifluoromethyl)cyclopropyl)methanol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
rac-[(1R,2R)-2-(trifluoromethyl)cyclopropyl]methanol
100mg
$ 350.00

Apolloscientific
(+/-)-(2-trans-(Trifluoromethyl)cyclopropyl)methanol
100mg
$ 714.00

American Custom Chemicals Corporation
(+/-)-(2-TRANS-(TRIFLUOROMETHYL)CYCLOPROPYL)METHANOL 95.00%
5MG
$ 497.84

AK Scientific
[(1S,2S)-2-(Trifluoromethyl)cyclopropyl]methanol
100mg
$ 453.00

Total 10 raw suppliers

Chemical Property of (trans-2-(Trifluoromethyl)cyclopropyl)methanol

Chemical Property:

PSA：20.23000
LogP:1.17710
XLogP3:1.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:1
Exact Mass:140.04489933
Heavy Atom Count:9
Complexity:109

Purity/Quality:

97% ^*data from raw suppliers

rac-[(1R,2R)-2-(trifluoromethyl)cyclopropyl]methanol ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1C(C1C(F)(F)F)CO
Isomeric SMILES:C1[C@H]([C@@H]1C(F)(F)F)CO

Technology Process of (trans-2-(Trifluoromethyl)cyclopropyl)methanol

There total 5 articles about (trans-2-(Trifluoromethyl)cyclopropyl)methanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

: 22581-33-5,78376-99-5
(±)-trans-2-(trifluoromethyl)cyclopropane-1-carboxylic acid

: 22666-34-8,78376-92-8
trans-2-trifluoromethylcyclopropylmethanol

Guidance literature:: With lithium aluminium tetrahydride; In diethyl ether; at -78 ℃; for 2.5h;
DOI:10.3762/bjoc.10.302

Reference yield:

: 70961-05-6
4-trifluoromethyl-4-oxobutyric acid ethyl ester

: 22666-34-8,78376-92-8
trans-2-trifluoromethylcyclopropylmethanol

Guidance literature:: Multi-step reaction with 4 steps

1: 95 percent / hydrogen / platinum oxide / diethyl ether / 760 Torr

3: 65 percent / potassium t-butoxide / dimethylsulfoxide

4: 75 percent / lithium aluminium hydride / diethyl ether / 16 h / Heating

With lithium aluminium tetrahydride; potassium tert-butylate; hydrogen; platinum(IV) oxide; In diethyl ether; dimethyl sulfoxide;

Reference yield:

: 94633-25-7
ethyl 5,5,5-trifluoro-4-oxo-3-ethoxycarbonyl-pentanoate

: 22666-34-8,78376-92-8
trans-2-trifluoromethylcyclopropylmethanol

Guidance literature:: Multi-step reaction with 5 steps

1: 62 percent / boric acid / 3 h / 170 °C / Heating

2: 95 percent / hydrogen / platinum oxide / diethyl ether / 760 Torr

4: 65 percent / potassium t-butoxide / dimethylsulfoxide

5: 75 percent / lithium aluminium hydride / diethyl ether / 16 h / Heating

With lithium aluminium tetrahydride; potassium tert-butylate; hydrogen; boric acid; platinum(IV) oxide; In diethyl ether; dimethyl sulfoxide;