N-[4-(trifluoromethyl)phenyl]-D-valine

Base Information

Chemical Name:N-[4-(trifluoromethyl)phenyl]-D-valine
CAS No.:78445-41-7
Molecular Formula:C12H14F3NO2
Molecular Weight:261.244
Hs Code.:
DSSTox Substance ID:DTXSID10539078
Wikidata:Q82414715

Synonyms:N-[4-(trifluoromethyl)phenyl]-D-valine;78445-41-7;SCHEMBL1259765;(R)-2-(4-trifluoromethylphenylamino)-3-methylbutanoic acid;DTXSID10539078;NZPWGWAEKDSVFN-SNVBAGLBSA-N

Suppliers and Price of N-[4-(trifluoromethyl)phenyl]-D-valine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of N-[4-(trifluoromethyl)phenyl]-D-valine

Chemical Property:

XLogP3:3.7
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:4
Exact Mass:261.09766318
Heavy Atom Count:18
Complexity:284

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)C(C(=O)O)NC1=CC=C(C=C1)C(F)(F)F
Isomeric SMILES:CC(C)[C@H](C(=O)O)NC1=CC=C(C=C1)C(F)(F)F

Technology Process of N-[4-(trifluoromethyl)phenyl]-D-valine

There total 2 articles about N-[4-(trifluoromethyl)phenyl]-D-valine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 46.0%

: 640-68-6,25609-85-2,7004-03-7,921-10-8
D-Val-OH

: 455-13-0
4-Iodobenzotrifluoride

: 78445-41-7
(R)-2-(4-trifluoromethylphenylamino)-3-methylbutanoic acid

Guidance literature:: With potassium carbonate; copper(l) iodide; In N,N-dimethyl acetamide; at 90 ℃; for 48h;

Reference yield:

: 455-14-1
4-trifluoromethylphenylamine

: 76792-22-8,10323-40-7,26782-75-2,565-74-2
(R)-2-bromoisovaleric acid

: 78445-41-7
(R)-2-(4-trifluoromethylphenylamino)-3-methylbutanoic acid

Guidance literature:: With potassium hydroxide; sodium hydroxide; In methanol;

Reference yield: 47.0%

: 78445-41-7
(R)-2-(4-trifluoromethylphenylamino)-3-methylbutanoic acid

: 866831-47-2
(2R)-3-methyl-2-{[4-(trifluoromethyl)phenyl]amino}butan-1-ol

Guidance literature:: (R)-2-(4-trifluoromethylphenylamino)-3-methylbutanoic acid; With chloroformic acid ethyl ester; triethylamine; In tetrahydrofuran; Cooling;

With sodium tetrahydroborate; In tetrahydrofuran; at 0 - 20 ℃;