5-Methyl-2,3-diphenylpyrazine

Base Information

• Chemical Name: 5-Methyl-2,3-diphenylpyrazine
• CAS No.: 78605-07-9
• Molecular Formula: C17H14N2
• Molecular Weight: 246.312
• DSSTox Substance ID: DTXSID00505767
• Nikkaji Number: J855.278I
• Wikidata: Q82361068
• Mol file: 78605-07-9.mol

Synonyms:5-Methyl-2,3-diphenylpyrazine;78605-07-9;SCHEMBL2684042;DTXSID00505767

Chemical Property of 5-Methyl-2,3-diphenylpyrazine

Chemical Property:

• XLogP3: 3.5
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 2
• Exact Mass: 246.115698455
• Heavy Atom Count: 19
• Complexity: 266

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=CN=C(C(=N1)C2=CC=CC=C2)C3=CC=CC=C3

Technology Process of 5-Methyl-2,3-diphenylpyrazine

There total 7 articles about 5-Methyl-2,3-diphenylpyrazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

1,2-diaminopropan (78-90-0,10424-38-1) + benzil (134-81-6) → 2,3-diphenyl-5-methyl pyrazine (78605-07-9)

Guidance literature:

With γ-maghemite-silica nanocomposite; In neat (no solvent); at 55 ℃; for 6h; Green chemistry;

DOI:10.1016/j.catcom.2013.06.026

Reference yield: 88.0%

2-chloro-5,6-diphenylpyrazine (41270-66-0) + trimethylaluminum (75-24-1) → 2,3-diphenyl-5-methyl pyrazine (78605-07-9)

Guidance literature:

With tetrakis(triphenylphosphine) palladium⁽⁰⁾; In 1,4-dioxane; hexane; for 2h; Heating;

Reference yield: 86.0%

2-hydroxy-2-phenylacetophenone (119-53-9,579-44-2) + 1,2-diaminopropan (78-90-0,10424-38-1) → 2,3-diphenyl-5-methyl pyrazine (78605-07-9)

Guidance literature:

With γ-maghemite-silica nanocomposite; In neat (no solvent); at 55 ℃; for 6h; Green chemistry;

DOI:10.1016/j.catcom.2013.06.026

upstream raw materials:

2,3-dihydro-2-methyl-5,6-diphenylpyrazine

2-chloro-5,6-diphenylpyrazine

trimethylaluminum

2-hydroxy-2-phenylacetophenone

Downstream raw materials:

2,3,6-triphenyl-5H-pyrrolo[2,3-b]pyrazine

(Z)-2-(5,6-Diphenyl-pyrazin-2-yl)-1-phenyl-ethenol

(Z)-2-(5,6-Diphenyl-pyrazin-2-yl)-1-phenyl-vinylamine