Ethyl 2-(2-bromo-1-methyl-1H-indol-3-yl)acetate

Base Information

Chemical Name:Ethyl 2-(2-bromo-1-methyl-1H-indol-3-yl)acetate
CAS No.:786704-07-2
Molecular Formula:C₁₃H₁₄BrNO₂
Molecular Weight:296.164
Hs Code.:2933990090
DSSTox Substance ID:DTXSID40462421
Wikidata:Q82286960
Mol file:786704-07-2.mol

Synonyms:786704-07-2;Ethyl 2-(2-bromo-1-methyl-1H-indol-3-yl)acetate;DTXSID40462421;Ethyl (2-bromo-1-methyl-1H-indol-3-yl)acetate;Ethyl2-(2-bromo-1-methyl-1H-indol-3-yl)acetate

Suppliers and Price of Ethyl 2-(2-bromo-1-methyl-1H-indol-3-yl)acetate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
Ethyl2-(2-bromo-1-methyl-1H-indol-3-yl)acetate 95+%
1g
$ 762.00

Chemenu
ethyl2-(2-bromo-1-methyl-1H-indol-3-yl)acetate 95%
1g
$ 720.00

Alichem
Ethyl2-(2-bromo-1-methyl-1H-indol-3-yl)acetate
1g
$ 638.60

Total 5 raw suppliers

Chemical Property of Ethyl 2-(2-bromo-1-methyl-1H-indol-3-yl)acetate

Chemical Property:

Vapor Pressure:1.84E-06mmHg at 25°C
Boiling Point:395.4oC at 760 mmHg
Flash Point:192.9oC
PSA：31.23000
Density:1.4g/cm3
LogP:3.04640
Storage Temp.:2-8°C
XLogP3:3.2
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:4
Exact Mass:295.02079
Heavy Atom Count:17
Complexity:285

Purity/Quality:

95+% ^*data from raw suppliers

Ethyl2-(2-bromo-1-methyl-1H-indol-3-yl)acetate 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC(=O)CC1=C(N(C2=CC=CC=C21)C)Br

Technology Process of Ethyl 2-(2-bromo-1-methyl-1H-indol-3-yl)acetate

There total 2 articles about Ethyl 2-(2-bromo-1-methyl-1H-indol-3-yl)acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

: 1912-37-4
(2-bromo-1H-indol-3-yl)-acetic acid ethyl ester

: 74-88-4
methyl iodide

: 786704-07-2
(2-bromo-1-methyl-1H-indol-3-yl)-acetic acid ethyl ester

Guidance literature:: With sodium hydride; In acetonitrile; for 2h;
DOI:10.1021/jo047834a

Reference yield:

: 778-82-5
ethyl 3-indoleacetate

: 786704-07-2
(2-bromo-1-methyl-1H-indol-3-yl)-acetic acid ethyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 95 percent / N-bromo succinimide / CH₂Cl₂ / 3 h / 0 °C

2: 97 percent / sodium hydride / acetonitrile / 2 h

With N-Bromosuccinimide; sodium hydride; In dichloromethane; acetonitrile;
DOI:10.1021/ol048915w