6-Chloro-1-oxo-2,3-diphenyl-1lambda~5~-pyrazine

Base Information

• Chemical Name: 6-Chloro-1-oxo-2,3-diphenyl-1lambda~5~-pyrazine
• CAS No.: 78754-79-7
• Molecular Formula: C16H11ClN2O
• Molecular Weight: 282.729
• DSSTox Substance ID: DTXSID80508332
• Wikidata: Q82365160
• Mol file: 78754-79-7.mol

Synonyms:78754-79-7;6-Chloro-1-oxo-2,3-diphenyl-1lambda~5~-pyrazine;DTXSID80508332

Chemical Property of 6-Chloro-1-oxo-2,3-diphenyl-1lambda~5~-pyrazine

Chemical Property:

• XLogP3: 3.1
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 2
• Exact Mass: 282.0559907
• Heavy Atom Count: 20
• Complexity: 303

Purity/Quality:

85.0-99.8% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: C1=CC=C(C=C1)C2=NC=C([N+](=C2C3=CC=CC=C3)[O-])Cl

Technology Process of 6-Chloro-1-oxo-2,3-diphenyl-1lambda~5~-pyrazine

There total 1 articles about 6-Chloro-1-oxo-2,3-diphenyl-1lambda~5~-pyrazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 36.0%

2,3-diphenyl-pyrazine-1,4-dioxide (78754-78-6) → 5,6-Dichloro-2,3-diphenylpyrazine (57038-62-7) + 2-chloro-5,6-diphenylpyrazine 1-oxide (78754-79-7)

Guidance literature:

With trichlorophosphate; for 1h; Heating;

Reference yield: 100.0%

2-chloro-5,6-diphenylpyrazine 1-oxide (78754-79-7) → 5,6-diphenyl-1-hydroxy-2-oxo-1,2-dihydropyrazine (78754-80-0)

Guidance literature:

With sodium hydroxide; In ethanol; for 3h; Heating;

Reference yield: 76.0%

trimethylaluminum (75-24-1) + 2-chloro-5,6-diphenylpyrazine 1-oxide (78754-79-7) → 2,3-diphenyl-6-methylpyrazine 1-oxide (96549-07-4)

Guidance literature:

With tetrakis(triphenylphosphine) palladium⁽⁰⁾; In 1,4-dioxane; hexane; for 2h; Heating;

upstream raw materials:

2,3-diphenyl-pyrazine-1,4-dioxide

Downstream raw materials:

2,6-diphenylpyrazine 1-oxide

2,5,6-triphenylpyrazine 1-oxide

2,3-diphenyl-6-methylpyrazine 1-oxide

5,6-diphenyl-1-hydroxy-2-oxo-1,2-dihydropyrazine