4-FluoroMethylpiperidine hydrochloride

Base Information

Chemical Name:4-FluoroMethylpiperidine hydrochloride
CAS No.:787564-27-6
Molecular Formula:C6H12FN.ClH
Molecular Weight:153.627
Hs Code.:2933399090
Mol file:787564-27-6.mol

Synonyms:

Suppliers and Price of 4-FluoroMethylpiperidine hydrochloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
4-fluoromethylpiperidinehydrochloride
100mg
$ 220.00

Matrix Scientific
4-Fluoromethylpiperidine hydrochloride >95%
1g
$ 700.00

Crysdot
4-(Fluoromethyl)piperidinehydrochloride 95+%
1g
$ 465.00

Apolloscientific
4-Fluoromethylpiperidinehydrochloride
1g
$ 525.00

AK Scientific
4-Fluoromethylpiperidinehydrochloride
500mg
$ 664.00

Activate Scientific
4-FluoromethylpiperidineHCl 95+%
250 mg
$ 225.00

Total 11 raw suppliers

Chemical Property of 4-FluoroMethylpiperidine hydrochloride

Chemical Property:

PSA：12.03000
LogP:2.08630

Purity/Quality:

97% ^*data from raw suppliers

4-fluoromethylpiperidinehydrochloride ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 4-FluoroMethylpiperidine hydrochloride

There total 4 articles about 4-FluoroMethylpiperidine hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 787564-27-6
4-(fluoromethyl)piperidine hydrochloride

Guidance literature:

Reference yield:

: 259143-03-8
tert-butyl 4-(fluoromethyl)piperidine-1-carboxylate

: 787564-27-6
4-(fluoromethyl)piperidine hydrochloride

Guidance literature:: With hydrogenchloride; In 1,4-dioxane; at 20 ℃; Cooling with ice;
DOI:10.1021/acsmedchemlett.8b00414

Reference yield:

: 123855-51-6
tert-butyl 4-(hydroxymethyl)piperidin-1-carboxylate

: 787564-27-6
4-(fluoromethyl)piperidine hydrochloride

Guidance literature:: Multi-step reaction with 3 steps

1: triethylamine / dichloromethane / 3 h / 0 - 20 °C / Inert atmosphere

2: tetrabutyl ammonium fluoride / tetrahydrofuran / Reflux

3: hydrogenchloride / 1,4-dioxane / 20 °C / Cooling with ice

With hydrogenchloride; tetrabutyl ammonium fluoride; triethylamine; In tetrahydrofuran; 1,4-dioxane; dichloromethane;
DOI:10.1021/acsmedchemlett.8b00414