1-Cyclohexyl-4-(trimethylsilyl)-3-butyn-1-ol

Base Information

Chemical Name:1-Cyclohexyl-4-(trimethylsilyl)-3-butyn-1-ol
CAS No.:79015-64-8
Molecular Formula:C13H24OSi
Molecular Weight:224.418
Hs Code.:
DSSTox Substance ID:DTXSID801205778
Nikkaji Number:J509.097K

Synonyms:1-Cyclohexyl-4-(trimethylsilyl)-3-butyn-1-ol;DTXSID801205778;AKOS024330428;alpha-[3-(Trimethylsilyl)-2-propyn-1-yl]cyclohexanemethanol;79015-64-8

Suppliers and Price of 1-Cyclohexyl-4-(trimethylsilyl)-3-butyn-1-ol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 1-Cyclohexyl-4-(trimethylsilyl)-3-butyn-1-ol

Chemical Property:

Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:3
Exact Mass:224.159641919
Heavy Atom Count:15
Complexity:247

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C[Si](C)(C)C#CCC(C1CCCCC1)O

Technology Process of 1-Cyclohexyl-4-(trimethylsilyl)-3-butyn-1-ol

There total 12 articles about 1-Cyclohexyl-4-(trimethylsilyl)-3-butyn-1-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

: 38002-45-8
3-bromo-1-(trimethylsilyl)-1-propyne

: 2043-61-0
cyclohexanecarbaldehyde

: 79015-64-8
1-cyclohexyl-4-trimethylsilanyl-but-3-yn-1-ol

Guidance literature:: With indium; indium(III) trifluoride; In tetrahydrofuran; for 9h; Heating;
DOI:10.1021/ja037410i

Reference yield: 44.0%

: 71321-17-0
methanesulfonic acid 3-trimethylsilyl-propyn-2-ynyl ester

: 2043-61-0
cyclohexanecarbaldehyde

: 79015-64-8
1-cyclohexyl-4-trimethylsilanyl-but-3-yn-1-ol

Guidance literature:: With tin(IV) iodide; tetra-(n-butyl)ammonium iodide; In dichloromethane; at 20 ℃; for 72h;
DOI:10.1055/s-2006-944222

Reference yield:

: 129217-85-2
trimethyl (3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)prop-1-yn-1-yl)silane

: 2043-61-0
cyclohexanecarbaldehyde

: 79015-64-8
1-cyclohexyl-4-trimethylsilanyl-but-3-yn-1-ol

Guidance literature:: trimethyl (3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)prop-1-yn-1-yl)silane; cyclohexanecarbaldehyde; With diethylzinc; In tetrahydrofuran; toluene; at 20 ℃; for 0.75h; Inert atmosphere;

With hydrogenchloride; In tetrahydrofuran; water; toluene; for 0.5h; Inert atmosphere;
DOI:10.1021/ol902457m