1H-Carbazole-1-acetic acid, 9-[(1S)-1-(4-chlorophenyl)ethyl]-6-fluoro-2,3,4,9-tetrahydro-8-(methylsulf onyl)-, (1R)-

Base Information

Chemical Name:1H-Carbazole-1-acetic acid, 9-[(1S)-1-(4-chlorophenyl)ethyl]-6-fluoro-2,3,4,9-tetrahydro-8-(methylsulf onyl)-, (1R)-
CAS No.:794535-38-9
Molecular Formula:C23H23ClFNO4S
Molecular Weight:463.957
Hs Code.:

Synonyms:

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Chemical Property of 1H-Carbazole-1-acetic acid, 9-[(1S)-1-(4-chlorophenyl)ethyl]-6-fluoro-2,3,4,9-tetrahydro-8-(methylsulf onyl)-, (1R)-

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Technology Process of 1H-Carbazole-1-acetic acid, 9-[(1S)-1-(4-chlorophenyl)ethyl]-6-fluoro-2,3,4,9-tetrahydro-8-(methylsulf onyl)-, (1R)-

There total 15 articles about 1H-Carbazole-1-acetic acid, 9-[(1S)-1-(4-chlorophenyl)ethyl]-6-fluoro-2,3,4,9-tetrahydro-8-(methylsulf onyl)-, (1R)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 794535-42-5
ethyl [(1R)-9-[(1S)-1-(4-chlorophenyl)ethyl]-6-fluoro-8-(methylsulfonyl)-2,3,4,9-tetrahydro-1H-carbazol-1-yl]acetate

: 794535-38-9
[(1R)-9-[(1S)-1-(4-chlorophenyl)ethyl]-6-fluoro-8-(methylsulfonyl)-2,3,4,9-tetrahydro-1H-carbazol-1-yl] acetatic acid

: 854738-76-4
[(1S)-9-[(1S)-1-(4-chlorophenyl)ethyl]-6-fluoro-8-(methylsulfonyl)-2,3,4,9-tetrahydro-1H-carbazol-1-yl]acetatic acid

Guidance literature:: ethyl [(1R)-9-[(1S)-1-(4-chlorophenyl)ethyl]-6-fluoro-8-(methylsulfonyl)-2,3,4,9-tetrahydro-1H-carbazol-1-yl]acetate; With methanol; lithium hydroxide; water; In tetrahydrofuran; at 20 ℃; for 2h;

With acetic acid; In tetrahydrofuran; water;

Reference yield:

: 64-19-7,77671-22-8
acetic acid

: 794535-38-9
[(1R)-9-[(1S)-1-(4-chlorophenyl)ethyl]-6-fluoro-8-(methylsulfonyl)-2,3,4,9-tetrahydro-1H-carbazol-1-yl] acetatic acid

Guidance literature:: ethyl [9-[(1S)-1-(4-chlorophenyl)ethyl]-6-fluoro-8-(methylsulfonyl)-2,3,4,9-tetrahydro-1H-carbazol-1-yl]acetate; With lithium hydroxide; water; In tetrahydrofuran; methanol; at 0 ℃; for 12h;

acetic acid; In tetrahydrofuran; methanol;

Reference yield:

: 794535-42-5
ethyl [(1R)-9-[(1S)-1-(4-chlorophenyl)ethyl]-6-fluoro-8-(methylsulfonyl)-2,3,4,9-tetrahydro-1H-carbazol-1-yl]acetate

: 794535-38-9
[(1R)-9-[(1S)-1-(4-chlorophenyl)ethyl]-6-fluoro-8-(methylsulfonyl)-2,3,4,9-tetrahydro-1H-carbazol-1-yl] acetatic acid

Guidance literature:: ethyl [(1R)-9-[(1S)-1-(4-chlorophenyl)ethyl]-6-fluoro-8-(methylsulfonyl)-2,3,4,9-tetrahydro-1H-carbazol-1-yl]acetate; With lithium hydroxide; water; In tetrahydrofuran; methanol; at 20 ℃; for 2h;

With acetic acid; In tetrahydrofuran; methanol;