6β-Methylpregn-4-ene-3,20-dione

Base Information

Chemical Name:6β-Methylpregn-4-ene-3,20-dione
CAS No.:2300-06-3
Molecular Formula:C22H32O2
Molecular Weight:328.4883
Hs Code.:
Mol file:2300-06-3.mol

Synonyms:6alpha-Methylprednisone;methylprednisone;6-Methylprednisone;6|A-Methyl Prednisone;

Suppliers and Price of 6β-Methylpregn-4-ene-3,20-dione

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemical Property of 6β-Methylpregn-4-ene-3,20-dione

Chemical Property:

Vapor Pressure:2.03E-08mmHg at 25°C
Boiling Point:453.7°Cat760mmHg
Flash Point:169°C
PSA：34.14000
Density:1.07g/cm³
LogP:4.96950

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 6β-Methylpregn-4-ene-3,20-dione

There total 13 articles about 6β-Methylpregn-4-ene-3,20-dione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 60.0%

: 14423-36-0
5α-hydroxy-6β-methylpregnan-3,20-dione

: 2300-06-3
6β-methylprogesterone

Guidance literature:: With pyridine; thionyl chloride; at 0 ℃;
DOI:10.1124/MOLPHARM.121.000349

Reference yield:

: 57-83-0
Progesterone

: 2300-06-3
6β-methylprogesterone

Guidance literature:: Multi-step reaction with 5 steps

1: toluene-4-sulfonic acid / toluene / 24 h / 145 °C / Dean-Stark

2: 3-chloro-benzenecarboperoxoic acid; sodium hydrogencarbonate / dichloromethane / 20 °C / Darkness

3: tetrahydrofuran / Reflux

4: hydrogenchloride / tetrahydrofuran / 3 h / 20 °C

5: thionyl chloride; pyridine / 0 °C

With pyridine; hydrogenchloride; thionyl chloride; sodium hydrogencarbonate; toluene-4-sulfonic acid; 3-chloro-benzenecarboperoxoic acid; In tetrahydrofuran; dichloromethane; toluene;
DOI:10.1124/MOLPHARM.121.000349

Reference yield:

: C₂₅H₃₈O₄

: 2300-06-3
6β-methylprogesterone

Guidance literature:: Multi-step reaction with 4 steps

1: 3-chloro-benzenecarboperoxoic acid; sodium hydrogencarbonate / dichloromethane / 20 °C / Darkness

2: tetrahydrofuran / Reflux

3: hydrogenchloride / tetrahydrofuran / 3 h / 20 °C

4: thionyl chloride; pyridine / 0 °C

With pyridine; hydrogenchloride; thionyl chloride; sodium hydrogencarbonate; 3-chloro-benzenecarboperoxoic acid; In tetrahydrofuran; dichloromethane;
DOI:10.1124/MOLPHARM.121.000349