Methylbenzylphenylphosphine oxide

Base Information

• Chemical Name: Methylbenzylphenylphosphine oxide
• CAS No.: 33838-34-5
• Molecular Formula: C14H15 O P
• Molecular Weight: 230.246
• NSC Number: 115681
• DSSTox Substance ID: DTXSID50903234
• Nikkaji Number: J726.099G
• Mol file: 33838-34-5.mol

Synonyms:33838-34-5;NSC115681;NoName_3863;(benzyl-methylphosphoryl)benzene;SCHEMBL9762821;Methyl-phenyl-benzyl-phosphinoxid;DTXSID50903234;NSC-115681

Chemical Property of Methylbenzylphenylphosphine oxide

Chemical Property:

• Vapor Pressure: 7.78E-07mmHg at 25°C
• Boiling Point: 418.8°Cat760mmHg
• Flash Point: 207.1°C
• Density: 1.1g/cm³
• XLogP3: 2.4
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 3
• Exact Mass: 230.086052095
• Heavy Atom Count: 16
• Complexity: 250

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CP(=O)(CC1=CC=CC=C1)C2=CC=CC=C2

Technology Process of Methylbenzylphenylphosphine oxide

There total 16 articles about Methylbenzylphenylphosphine oxide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

Benzyl-methyl-phenyl-phosphin (23275-37-8,25140-53-8,34868-25-2) → methylbenzylphenylphosphine oxide (33838-34-5)

Guidance literature:

With tert.-butylhydroperoxide; In methanol;

DOI:10.1021/ja00352a035

Reference yield: 85.0%

Methyl-phenyl-benzyl-phosphinsulfid → methylbenzylphenylphosphine oxide (33838-34-5)

Guidance literature:

With ozone; In methanol; hexane; at -40 - -20 ℃; for 0.166667h;

Reference yield: 82.0%

benzyl (phenyl)phosphine oxide (20335-99-3,20428-90-4,177334-60-0) + methyl iodide (74-88-4) → methylbenzylphenylphosphine oxide (33838-34-5)

Guidance literature:

benzyl (phenyl)phosphine oxide; With sodium hydride; In tetrahydrofuran; mineral oil; at 20 ℃; Inert atmosphere;

methyl iodide; In tetrahydrofuran; mineral oil; Inert atmosphere;

DOI:10.1016/j.tet.2011.09.045

upstream raw materials:

menthyl methylphenylphosphinate

benzyl chloride

ethyl hyponitrite

R(+)-Benzyl-methyl-phenyl-phosphin

Downstream raw materials:

Benzyl-methyl-phenyl-phosphin