RA VII

Base Information

• Chemical Name: RA VII
• CAS No.: 86229-97-2
• Molecular Formula: C₄₁H₅₀N₆O₉
• Molecular Weight: 770.883
• UNII: HVM25O0351
• DSSTox Substance ID: DTXSID701006656
• Nikkaji Number: J687.498C
• Wikidata: Q27280126
• Metabolomics Workbench ID: 130044
• ChEMBL ID: CHEMBL289601
• Mol file: 86229-97-2.mol

Synonyms:RA 700;RA VII;RA-700;RA-VII

Chemical Property of RA VII

Chemical Property:

• Vapor Pressure: 0mmHg at 25°C
• Boiling Point: 1079.1°C at 760 mmHg
• Flash Point: 606.4°C
• PSA: 186.39000
• Density: 1.165g/cm³
• LogP: 2.48750
• XLogP3: 3.3
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 9
• Rotatable Bond Count: 4
• Exact Mass: 770.36392719
• Heavy Atom Count: 56
• Complexity: 1420

Purity/Quality:

99% ^*data from raw suppliers

RAVII ≥98% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1C(=O)NC(C(=O)N(C(C(=O)NC(C(=O)N(C2CC3=CC=C(C=C3)OC4=C(C=CC(=C4)CC(C(=O)N1)N(C2=O)C)OC)C)C)CC5=CC=C(C=C5)OC)C)C
• Isomeric SMILES: C[C@@H]1C(=O)N[C@H](C(=O)N([C@H](C(=O)N[C@H](C(=O)N([C@H]2CC3=CC=C(C=C3)OC4=C(C=CC(=C4)C[C@@H](C(=O)N1)N(C2=O)C)OC)C)C)CC5=CC=C(C=C5)OC)C)C

Technology Process of RA VII

There total 61 articles about RA VII which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 74.0%

C41H48N6O8 (333971-05-4) → RA-VII (122621-60-7,144993-87-3,144993-88-4,86229-97-2) + [D-Ala-4]RA-VII

Guidance literature:

With boron trifluoride diethyl etherate; In water; acetonitrile; at 50 ℃;

DOI:10.1016/S0040-4039(00)02279-6

Reference yield: 61.0%

C41H48N6O8 (562834-36-0) → RA-VII (122621-60-7,144993-87-3,144993-88-4,86229-97-2) + [L-Ala-1]RA-VII

Guidance literature:

With boron trifluoride diethyl etherate; water; In acetonitrile; at 20 ℃; for 24h;

DOI:10.1021/ja021131y

Reference yield: 60.0%

C41H48N6O7S → RA-VII (122621-60-7,144993-87-3,144993-88-4,86229-97-2) + [D-Ala-2]RA-VII

Guidance literature:

With boron trifluoride diethyl etherate; water; In acetonitrile; at 50 ℃; for 48h;

DOI:10.1021/ja021131y

upstream raw materials:

methyl bromide

deoxybouvadin

C₄₁H₅₂N₆O₁₀

diazomethyl-trimethyl-silane

Downstream raw materials:

deoxybouvadin

C₄₁H₄₄F₆N₆O₁₃S₂

C₄₁H₄₉N₇O₁₁

C₄₂H₅₂N₆O₉