4-Amino-7-beta-D-arabinofuranosyl-7H-pyrrolo(3,2-d)pyrimidine

Base Information

Chemical Name:4-Amino-7-beta-D-arabinofuranosyl-7H-pyrrolo(3,2-d)pyrimidine
CAS No.:77691-03-3
Molecular Formula:C₁₁H₁₄N₄O₄
Molecular Weight:266.257
Hs Code.:
NSC Number:352890
DSSTox Substance ID:DTXSID50998882
ChEMBL ID:CHEMBL1991619

Synonyms:9-deazaadenosine;C9Ado

Suppliers and Price of 4-Amino-7-beta-D-arabinofuranosyl-7H-pyrrolo(3,2-d)pyrimidine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
9-DEAZAADENOSINE 95.00%
5MG
$ 498.65

Total 2 raw suppliers

Chemical Property of 4-Amino-7-beta-D-arabinofuranosyl-7H-pyrrolo(3,2-d)pyrimidine

Chemical Property:

Vapor Pressure:1.07E-19mmHg at 25°C
Boiling Point:684.8°C at 760 mmHg
Flash Point:368°C
PSA：137.51000
Density:1.688g/cm³
LogP:0.07730
Hydrogen Bond Donor Count:6
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:2
Exact Mass:302.0781827
Heavy Atom Count:20
Complexity:334

Purity/Quality:: 9-DEAZAADENOSINE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=C(C2=C(N1)C(=NC=N2)N)C3C(C(C(O3)CO)O)O.Cl

Technology Process of 4-Amino-7-beta-D-arabinofuranosyl-7H-pyrrolo(3,2-d)pyrimidine

There total 6 articles about 4-Amino-7-beta-D-arabinofuranosyl-7H-pyrrolo(3,2-d)pyrimidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 83348-75-8
2-Formyl-2-(2,3-O-isopropyliden-5-O-trityl-D-ribofuranosyl)acetonitril

: 77691-03-3,77702-03-5,110269-63-1
9-deazaadenosine

Guidance literature:: Multi-step reaction with 5 steps

1: sodium acetate / H₂O; methanol / 20 h / 25 °C

2: 1.) 1,5-diazabicyclo<4,3,0>nonene-5 2.) 1,5-diazabicyclo<4,3,0>nonene-5 / 1.) methylene chloride, 0 deg C, 1 h 2.) 25 deg C, 20 h

3: sodium carbonate / methanol / 0.83 h / 25 °C

4: ethanol / 5 h / Heating

5: 12percent HCl/MeOH

With hydrogenchloride; methanol; DBN; sodium acetate; sodium carbonate; In methanol; ethanol; water;
DOI:10.1016/0040-4039(81)80031-7

Reference yield:

: 77690-98-3,86194-67-4,86194-68-5
(E)-3-(Cyanomethyl-amino)-2-((3aS,6R,6aR)-2,2-dimethyl-6-trityloxymethyl-tetrahydro-furo[3,4-d][1,3]dioxol-4-yl)-acrylonitrile

: 77691-03-3,77702-03-5,110269-63-1
9-deazaadenosine

Guidance literature:: Multi-step reaction with 4 steps

1: 1.) 1,5-diazabicyclo<4,3,0>nonene-5 2.) 1,5-diazabicyclo<4,3,0>nonene-5 / 1.) methylene chloride, 0 deg C, 1 h 2.) 25 deg C, 20 h

2: sodium carbonate / methanol / 0.83 h / 25 °C

3: ethanol / 5 h / Heating

4: 12percent HCl/MeOH

With hydrogenchloride; methanol; DBN; sodium carbonate; In methanol; ethanol;
DOI:10.1016/0040-4039(81)80031-7

Reference yield:

: 77690-99-4,77691-04-4
3-Amino-2-cyano-4-((3aS,6R,6aR)-2,2-dimethyl-6-trityloxymethyl-tetrahydro-furo[3,4-d][1,3]dioxol-4-yl)-pyrrole-1-carboxylic acid ethyl ester

: 77691-03-3,77702-03-5,110269-63-1
9-deazaadenosine

Guidance literature:: Multi-step reaction with 3 steps

1: sodium carbonate / methanol / 0.83 h / 25 °C

2: ethanol / 5 h / Heating

3: 12percent HCl/MeOH

With hydrogenchloride; methanol; sodium carbonate; In methanol; ethanol;
DOI:10.1016/0040-4039(81)80031-7