83348-75-8Relevant academic research and scientific papers
SYNTHESIS OF FUROPYRIMIDINE NUCLEOSIDES: A NOVEL C-NUCLEOSIDE ISOSTERE OF ADENOSINE
Bhattacharya, Birendra K.,Lim, Mu-Ill,Otter, Brian A.,Klein, Robert S.
, p. 815 - 818 (2007/10/02)
The synthesis of 4-amino-7-(β-D-ribofuranosyl)-furopyrimidine, a new C-nucleoside analog of adenosine, is described.It involves base-catalyzed cyclization of the 2-(ribofuranosyl)-2-cyano ethers 3 to afford the ribosyl-3-amino-2-cyanofurans 4α and
SYNTHESIS OF THE PYRROLOPYRIMIDINE C-NUCLEOSIDE ISOSTERE OF INOSINE
Lim, Mu-Ill,Klein, Robert S.,Fox, Jack J.
, p. 1013 - 1016 (2007/10/02)
The synthesis of "9-deazainosine", a new C-nucleoside analog of inosine and of formycin B is described.It involves conversion of a ribosylated 3-amino-2-carboalkoxypyrrole intermediate to the desired pyrrolopyrimidine system.
