5-chloro-1H-pyrrolo[3,2-b]pyridine-2-carboxylic acid

Base Information

Chemical Name:5-chloro-1H-pyrrolo[3,2-b]pyridine-2-carboxylic acid
CAS No.:800401-63-2
Molecular Formula:C8H5ClN2O2
Molecular Weight:196.593
Hs Code.:2933990090
European Community (EC) Number:936-721-0,689-933-8
DSSTox Substance ID:DTXSID30470252
Wikidata:Q72459126
Mol file:800401-63-2.mol

Synonyms:5-chloro-1H-pyrrolo[3,2-b]pyridine-2-carboxylic acid;800401-63-2;5-CHLORO-4-AZAINDOLE-2-CARBOXYLIC ACID;MFCD18261123;SCHEMBL1202548;DTXSID30470252;LTAXMSVURJPVQV-UHFFFAOYSA-N;AKOS015949564;GF-0722;PB19602;SY259706;CS-0053831;FT-0747702;P12299;A864760;J-517259;5-Chloro-1H-pyrrolo[2,3-]pyridine-2-carboxylic acid;5-chloro-1H-pyrrolo[3,2-b]pyridine-2-carboxylicacid

Suppliers and Price of 5-chloro-1H-pyrrolo[3,2-b]pyridine-2-carboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
5-Chloro-1H-pyrrolo[3,2-B]pyridine-2-carboxylicAcid
2mg
$ 60.00

TRC
5-Chloro-1H-pyrrolo[3,2-B]pyridine-2-carboxylicAcid
1mg
$ 45.00

Matrix Scientific
5-Chloro-1H-pyrrolo[3,2-b]pyridine-2-carboxylic acid >95%
500mg
$ 522.00

Matrix Scientific
5-Chloro-1H-pyrrolo[3,2-b]pyridine-2-carboxylic acid >95%
1g
$ 648.00

Crysdot
5-Chloro-1H-pyrrolo[3,2-b]pyridine-2-carboxylicacid 95+%
5g
$ 630.00

Chemenu
5-Chloro-1H-pyrrolo[3,2-b]pyridine-2-carboxylicacid 95%+
1g
$ 286.00

Chemenu
5-Chloro-1H-pyrrolo[3,2-b]pyridine-2-carboxylicacid 95%+
250mg
$ 147.00

Chemenu
5-Chloro-1H-pyrrolo[3,2-b]pyridine-2-carboxylicacid 95%+
100mg
$ 88.00

American Custom Chemicals Corporation
5-CHLORO-1H-PYRROLO[3,2-B]PYRIDINE-2-CARBOXYLIC ACID 95.00%
5MG
$ 501.81

Ambeed
5-Chloro-1H-pyrrolo[3,2-b]pyridine-2-carboxylicacid 98+%
250mg
$ 34.00

Total 19 raw suppliers

Chemical Property of 5-chloro-1H-pyrrolo[3,2-b]pyridine-2-carboxylic acid

Chemical Property:

Melting Point:ca 295℃
Boiling Point:467.0±40.0 °C(Predicted)
PKA:2.74±0.30(Predicted)
PSA：65.98000
Density:1.644±0.06 g/cm3(Predicted)
LogP:1.91450
Storage Temp.:under inert gas (nitrogen or Argon) at 2-8°C
Water Solubility.:Insoluble in water.
XLogP3:1.9
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:196.0039551
Heavy Atom Count:13
Complexity:224

Purity/Quality:

99%, ^*data from raw suppliers

5-Chloro-1H-pyrrolo[3,2-B]pyridine-2-carboxylicAcid ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=NC2=C1NC(=C2)C(=O)O)Cl
Uses Used for pharmaceutical and cytokine signaling intermediates.

Technology Process of 5-chloro-1H-pyrrolo[3,2-b]pyridine-2-carboxylic acid

There total 9 articles about 5-chloro-1H-pyrrolo[3,2-b]pyridine-2-carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.6%

: 1050501-88-6
2-bromo-6-chloro-pyridin-3-amine

: 127-17-3
2-oxo-propionic acid

: 800401-63-2
5-chloro-1H-pyrrolo[3 ,2-b]pyridine-2-carboxylic acid

Guidance literature:: With palladium diacetate; triethylamine; In N,N-dimethyl-formamide; at 100 ℃;

Reference yield:

: 800401-62-1
ethyl 5-chloro-1H-pyrrolo[3,2-b]pyridine-2-carboxylate

: 800401-63-2
5-chloro-1H-pyrrolo[3 ,2-b]pyridine-2-carboxylic acid

Guidance literature:: ethyl 5-chloro-1H-pyrrolo[3,2-b]pyridine-2-carboxylate; With sodium hydroxide; ethanol; water; at 20 - 70 ℃; for 18h;

With acetic acid; pH=4;