4H-1-Benzopyran-4-one, 7-chloro-2,3-dihydro-2,2-dimethyl-

Base Information

• Chemical Name: 4H-1-Benzopyran-4-one, 7-chloro-2,3-dihydro-2,2-dimethyl-
• CAS No.: 80055-86-3
• Molecular Formula: C11H11ClO2
• Molecular Weight: 210.66
• Mol file: 80055-86-3.mol

Synonyms:7-chloro-2,2-dimethyl-2,3-dihydro-4H-chromen-4-one;7-chloro-3,4-dihydro-2,2-dimethyl-2H-1-benzopyran-4-one;7-chloro-2,2-dimethylchroman-4-one;7-Chloro-2,2-dimethyl-chroman-4-one;

Chemical Property of 4H-1-Benzopyran-4-one, 7-chloro-2,3-dihydro-2,2-dimethyl-

Chemical Property:

• Melting Point: 69 - 70 °C
• PSA: 26.30000
• LogP: 3.08380

Purity/Quality:

97% ^*data from raw suppliers

7-Chloro-2,2-dimethylchroman-4-one ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4H-1-Benzopyran-4-one, 7-chloro-2,3-dihydro-2,2-dimethyl-

There total 7 articles about 4H-1-Benzopyran-4-one, 7-chloro-2,3-dihydro-2,2-dimethyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 79.0%

4-chloro-2-hydroxy acetophenone (6921-66-0) + acetone (67-64-1) → 7-chloro-2,2-dimethylchroman-4-one (80055-86-3)

Guidance literature:

4-chloro-2-hydroxy acetophenone; acetone; With pyrrolidine; In methanol; at 25 ℃;

With hydrogenchloride; In water; pH=1;

Reference yield: 79.0%

4-methyl-pent-3-en-2-one (141-79-7) + 4-chloro-2-hydroxy acetophenone (6921-66-0) → 7-chloro-2,2-dimethylchroman-4-one (80055-86-3)

Guidance literature:

With pyrrolidine; In toluene; 1) 24 h, 2) heating;

Reference yield: 50.0%

3'-chlorophenyl 3-methylbut-2-enoate (142337-53-9) → 5-chloro-2,2-dimethylchroman-4-one (80055-84-1) + 7-chloro-2,2-dimethylchroman-4-one (80055-86-3)

Guidance literature:

With potassium hydroxide; In cyclohexane; water; at 25 ℃; for 1.08333h; Inert atmosphere; Irradiation;

DOI:10.1016/j.tetlet.2014.06.081

upstream raw materials:

4-methyl-pent-3-en-2-one

4-chloro-2-hydroxy acetophenone

3'-chlorophenyl 3-methylbut-2-enoate

acetone