S-(2-aminoethyl)cysteine

Base Information

• Chemical Name: S-(2-aminoethyl)cysteine
• CAS No.: 2936-69-8
• Molecular Formula: C₅H₁₂N₂O₂S
• Molecular Weight: 164.228
• Hs Code.: 2930909090
• NSC Number: 115857,241277
• Nikkaji Number: J2.766.259E
• ChEMBL ID: CHEMBL2010208
• Mol file: 2936-69-8.mol

Synonyms:4-thia-L-lysine;4-thialysine;aminoethylcysteine;gamma-thia-Lys;gamma-thialysine;S-2-aminoethyl cysteine;S-2-aminoethyl cysteine dihydrochloride;S-2-aminoethyl cysteine hydrochloride;S-2-aminoethyl cysteine monohydrochloride;S-beta-aminoethyl cysteine;thialysine;thiosine

Chemical Property of S-(2-aminoethyl)cysteine

Chemical Property:

• Boiling Point: 341.1°Cat760mmHg
• PKA: 2.02±0.10(Predicted)
• Flash Point: 160.1°C
• PSA: 114.64000
• Density: g/cm³
• LogP: 0.49080
• XLogP3: -3.7
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 5
• Exact Mass: 164.06194880
• Heavy Atom Count: 10
• Complexity: 110

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C(CSCC(C(=O)O)N)N

Technology Process of S-(2-aminoethyl)cysteine

There total 6 articles about S-(2-aminoethyl)cysteine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

L-phosphoserine (407-41-0,7331-08-0) + Cysteamine (60-23-1) → S-(2-aminoethyl)-L-cysteine (2936-69-8)

Guidance literature:

With ethylenediaminetetraacetic acid; O-phospho-L-serine sulfhydrylase from Aeropyrum pernix K₁; In aq. phosphate buffer; at 60 ℃; for 0.166667h; pH=7.5; Enzymatic reaction;

DOI:10.1246/cl.170822

Reference yield:

ethyleneimine (151-56-4,9002-98-6) + l-cysteine hydrochloride (52-89-1) → S-(2-aminoethyl)-L-cysteine (2936-69-8)

Guidance literature:

In methanol;

Reference yield:

3-(2-p-toluenesulfonamidoethylthio) alanine (3981-22-4) → S-(2-aminoethyl)-L-cysteine (2936-69-8)

Guidance literature:

With ammonia; sodium amide;

DOI:10.1039/j39660001098

upstream raw materials:

ethyleneimine

l-cysteine hydrochloride

L-cystine

2-bromoethylamine hydrobromide

Downstream raw materials:

[2-((R)-2-Benzoylamino-2-carbamoyl-ethylsulfanyl)-ethyl]-carbamic acid benzyl ester

[2-((R)-2,5-dioxo-oxazolidin-4-ylmethylsulfanyl)-ethyl]-carbamic acid benzyl ester

(R)-2-Amino-3-(2-benzyloxycarbonylamino-ethylsulfanyl)-propionic acid methyl ester

2-(R)-thiomorpholine carboxylic acid hydrochloride