Ketone, 1-benzyl-2-indolyl hydroxymethyl-

Base Information

• Chemical Name: Ketone, 1-benzyl-2-indolyl hydroxymethyl-
• CAS No.: 52098-16-5
• Molecular Formula: C17H15NO2
• Molecular Weight: 265.312
• DSSTox Substance ID: DTXSID40200087
• Nikkaji Number: J96.770J
• Wikidata: Q83073121
• Mol file: 52098-16-5.mol

Synonyms:BRN 1475065;1-Benzyl-2-(hydroxyacetyl)indole;KETONE, 1-BENZYL-2-INDOLYL HYDROXYMETHYL-;1-Benzyl-2-indolyl hydroxymethyl ketone;52098-16-5;DTXSID40200087;LS-87050;2-Hydroxy-1-(1-benzyl-1H-indol-2-yl)ethanone

Chemical Property of Ketone, 1-benzyl-2-indolyl hydroxymethyl-

Chemical Property:

• Vapor Pressure: 2.25E-10mmHg at 25°C
• Boiling Point: 489°Cat760mmHg
• Flash Point: 249.5°C
• Density: 1.17g/cm³
• XLogP3: 3
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 4
• Exact Mass: 265.110278721
• Heavy Atom Count: 20
• Complexity: 338

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C=C1)CN2C3=CC=CC=C3C=C2C(=O)CO

Technology Process of Ketone, 1-benzyl-2-indolyl hydroxymethyl-

There total 1 articles about Ketone, 1-benzyl-2-indolyl hydroxymethyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ 1-(1-benzyl-indol-2-yl)-2-hydroxy-ethanone (52098-16-5)

Guidance literature:

2-Acetoxyacetyl-3-benzyl-indol in wss.-ethanol. H2SO4;

DOI:10.1007/BF00758396

Reference yield: 62.0%

ethyl bromide (74-96-4) + 1-(1-benzyl-indol-2-yl)-2-hydroxy-ethanone (52098-16-5) → C19H17NO2S

Guidance literature:

1-(1-benzyl-indol-2-yl)-2-hydroxy-ethanone; With sulfur; tetrabutylammomium bromide; potassium hydrogencarbonate; In water; N,N-dimethyl-formamide; at 90 ℃; for 10h; Inert atmosphere;

ethyl bromide; In water; N,N-dimethyl-formamide; for 2h;