4-cyano-1H-pyrrole-2-carboxylic Acid

Base Information

Chemical Name:4-cyano-1H-pyrrole-2-carboxylic Acid
CAS No.:80242-24-6
Molecular Formula:C6H4N2O2
Molecular Weight:136.11
Hs Code.:2933990090
European Community (EC) Number:800-109-0
DSSTox Substance ID:DTXSID90473002
Wikidata:Q82302184
Mol file:80242-24-6.mol

Synonyms:4-cyano-1H-pyrrole-2-carboxylic Acid;80242-24-6;4-Cyanopyrrole-2-carboxylic acid;MFCD09991904;1H-Pyrrole-2-carboxylic acid, 4-cyano-;4-cyanopyrrolecarboxylic acid;SCHEMBL1857408;DTXSID90473002;SAEZQFNKTQKVSM-UHFFFAOYSA-N;4-cyano-1H-pyrrole-2-carboxylicAcid;AKOS006311028;SB62256;SS-4585;SY192788;CS-0055015;FT-0722454;EN300-96737;4-Cyano-1H-pyrrole-2-carboxylic acid, AldrichCPR;A1-00753;Z1198267221

Suppliers and Price of 4-cyano-1H-pyrrole-2-carboxylic Acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
4-cyano-1H-pyrrole-2-carboxylicacid
50mg
$ 90.00

TRC
4-cyano-1H-pyrrole-2-carboxylicacid
10mg
$ 60.00

TRC
4-cyano-1H-pyrrole-2-carboxylicacid
5mg
$ 45.00

SynQuest Laboratories
4-Cyano-1H-pyrrole-2-carboxylic acid 97.0%
500 mg
$ 253.00

SynQuest Laboratories
4-Cyano-1H-pyrrole-2-carboxylic acid 97.0%
1 g
$ 336.00

Crysdot
4-Cyano-1H-pyrrole-2-carboxylicacid 97%
5g
$ 798.00

Crysdot
4-Cyano-1H-pyrrole-2-carboxylicacid 97%
1g
$ 290.00

Chemenu
4-Cyanopyrrole-2-carboxylicacid 95%+
250mg
$ 309.00

Chemenu
4-Cyanopyrrole-2-carboxylicacid 95%+
100mg
$ 161.00

Chemenu
4-Cyanopyrrole-2-carboxylicacid 95%+
5g
$ 1734.00

Total 16 raw suppliers

Chemical Property of 4-cyano-1H-pyrrole-2-carboxylic Acid

Chemical Property:

Vapor Pressure:0mmHg at 25°C
Melting Point:279℃ (decomposition)
Boiling Point:416.865oC at 760 mmHg
Flash Point:205.913oC
PSA：76.88000
Density:1.503g/cm3
LogP:0.58458
Storage Temp.:2-8°C
XLogP3:0.3
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:136.027277375
Heavy Atom Count:10
Complexity:193

Purity/Quality:

97% ^*data from raw suppliers

4-cyano-1H-pyrrole-2-carboxylicacid ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=C(NC=C1C#N)C(=O)O

Technology Process of 4-cyano-1H-pyrrole-2-carboxylic Acid

There total 3 articles about 4-cyano-1H-pyrrole-2-carboxylic Acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 80242-23-5
trichloroacetyl-(4-cyano-1H-pyrrol-2-yl)

: 80242-24-6
4-cyanopyrrole-2-carboxylic acid

Guidance literature:: With potassium hydroxide; water; 1) 0 deg C; 2) room temperature, 1.5 h;

Reference yield:

: 35302-72-8
pyrrol-2-yl trichloromethyl ketone

: 80242-24-6
4-cyanopyrrole-2-carboxylic acid

Guidance literature:: Multi-step reaction with 2 steps

1: 2.) DMF / 1.) acetonitrile, ice bath, to room temp., 12 h; 2.) ice bath then 50 deg C, 1 h then room temp., 3h

2: 92 percent / sodium hydroxide / 1.) ice bath; 2.) room temp., 2 h

With sodium hydroxide; N,N-dimethyl-formamide;