1H-Pyrazolo[4,3-h]quinazoline-3-carboxylic acid, 8-amino-4,5-dihydro-1-methyl-, ethyl ester

Base Information

Chemical Name:1H-Pyrazolo[4,3-h]quinazoline-3-carboxylic acid, 8-amino-4,5-dihydro-1-methyl-, ethyl ester
CAS No.:802534-49-2
Molecular Formula:C13H15N5O2
Molecular Weight:273.294
Hs Code.:

Synonyms:ethyl 8-amino1-methyl-4,5-dihydro-1H-pyrazolo[4,3-h]quinazoline-3-carboxylate;

Suppliers and Price of 1H-Pyrazolo[4,3-h]quinazoline-3-carboxylic acid, 8-amino-4,5-dihydro-1-methyl-, ethyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
Ethyl8-amino-1-methyl-4,5-dihydro-1H-pyrazolo[4,3-h]quinazoline-3-carboxylate 97%
5g
$ 982.00

Crysdot
Ethyl8-amino-1-methyl-4,5-dihydro-1H-pyrazolo[4,3-h]quinazoline-3-carboxylate 97%
1g
$ 327.00

Activate Scientific
Ethyl8-amino-1-methyl-4,5-dihydro-1H-pyrazolo[4,3-h]quinazoline-3-carboxylate 97%
250 mg
$ 241.00

Total 6 raw suppliers

Chemical Property of 1H-Pyrazolo[4,3-h]quinazoline-3-carboxylic acid, 8-amino-4,5-dihydro-1-methyl-, ethyl ester

Chemical Property:

PSA：95.92000
LogP:1.31580

Purity/Quality:

97% ^*data from raw suppliers

Ethyl8-amino-1-methyl-4,5-dihydro-1H-pyrazolo[4,3-h]quinazoline-3-carboxylate 97% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

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Technology Process of 1H-Pyrazolo[4,3-h]quinazoline-3-carboxylic acid, 8-amino-4,5-dihydro-1-methyl-, ethyl ester

There total 3 articles about 1H-Pyrazolo[4,3-h]quinazoline-3-carboxylic acid, 8-amino-4,5-dihydro-1-methyl-, ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

: ethyl (6E)-6-[(dimethylamino)methylidene]-1-methyl-7-oxo-4,5,6,7-tetrahydro-1H-indazole-3-carboxylate

: 50-01-1
guanidine hydrochloride

: 802534-49-2
ethyl 8-amino-1-methyl-4,5-dihydro-1H-pyrazolo[4,3-h]quinazoline-3-carboxylate

Guidance literature:: With potassium carbonate; In N,N-dimethyl-formamide; at 110 ℃; for 6h;
DOI:10.1021/jm9006559

Reference yield: 85.0%

: ethyl 6-[(dimethylamino)methylene]-1-methyl-7-oxo-4,5,6,7-tetrahydro-1H-indazole-3-carboxylate

: 50-01-1
guanidine hydrochloride

: 802534-49-2
ethyl 8-amino-1-methyl-4,5-dihydro-1H-pyrazolo[4,3-h]quinazoline-3-carboxylate

Guidance literature:: With sodium ethanolate; In ethanol; for 12h; Heating / reflux;

Reference yield:

: 802541-13-5
ethyl 1-methyl-7-oxo-4,5,6,7-tetrahydro-1H-indazole-3-carboxylate

: 802534-49-2
ethyl 8-amino-1-methyl-4,5-dihydro-1H-pyrazolo[4,3-h]quinazoline-3-carboxylate

Guidance literature:: Multi-step reaction with 2 steps

1: DMF (N,N-dimethyl-formamide) / 8 h / 60 °C

2: sodium ethanolate / ethanol / 12 h / Heating / reflux

With sodium ethanolate; In DMF (N,N-dimethyl-formamide); ethanol;