Benzothiazole, 2-(4-aminopyrazol-1-yl)- (8CI)

Base Information

• Chemical Name: Benzothiazole, 2-(4-aminopyrazol-1-yl)- (8CI)
• CAS No.: 28469-10-5
• Molecular Formula: C₁₀H₈N₄S
• Molecular Weight: 216.266
• Hs Code.: 2934999090
• Mol file: 28469-10-5.mol

Synonyms:Benzothiazole,2-(4-aminopyrazol-1-yl)- (8CI);1-(1,3-benzothiazol-2-yl)pyrazol-4-amine;1-(1,3-benzothiazol-2-yl)-1H-pyrazol-4-amine;2-(4-Aminopyrazol-1-yl)benzothiazole;Benzothiazole, 2-(4-aminopyrazol-1-yl)-;

Chemical Property of Benzothiazole, 2-(4-aminopyrazol-1-yl)- (8CI)

Chemical Property:

• Vapor Pressure: 1.11E-08mmHg at 25°C
• Refractive Index: 1.82
• Boiling Point: 461 °C at 760 mmHg
• Flash Point: 232.6 °C
• PSA: 84.97000
• Density: 1.54 g/cm³
• LogP: 2.64540

Purity/Quality:

99% ^*data from raw suppliers

BENZOTHIAZOLE, 2-(4-AMINOPYRAZOL-1-YL)- 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Benzothiazole, 2-(4-aminopyrazol-1-yl)- (8CI)

There total 2 articles about Benzothiazole, 2-(4-aminopyrazol-1-yl)- (8CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-(4-nitro-pyrazol-1-yl)-benzothiazole (28571-44-0) → 1-(1,3-benzothiazol-2-yl)-1H-pyrazol-4-amine (28469-10-5)

Guidance literature:

With hydrazine hydrate; nickel; In ethanol; Ambient temperature;

Reference yield:

1,3-benzothiazol-2-ylhydrazine (615-21-4) → 1-(1,3-benzothiazol-2-yl)-1H-pyrazol-4-amine (28469-10-5)

Guidance literature:

Multi-step reaction with 2 steps

1: acetic acid / 0.08 h / Heating

2: N₂H₄*H₂O / Raney-Ni / ethanol / Ambient temperature

With hydrazine hydrate; nickel; In ethanol; acetic acid;

Reference yield:

diethyl sulfate (64-67-5) + 1-(1,3-benzothiazol-2-yl)-1H-pyrazol-4-amine (28469-10-5) → 2-(4-Ethylamino-pyrazol-1-yl)-benzthiazol (28469-13-8)

Guidance literature:

With sodium carbonate; In methanol; Heating;

upstream raw materials:

2-(4-nitro-pyrazol-1-yl)-benzothiazole

1,3-benzothiazol-2-ylhydrazine

Downstream raw materials:

2-(4-Ethylamino-pyrazol-1-yl)-benzthiazol

Refernces