N-hydroxy-1-hydrazinecarboxamide

Base Information

• Chemical Name: N-hydroxy-1-hydrazinecarboxamide
• CAS No.: 21520-79-6
• Molecular Formula: CH5N3O2
• Molecular Weight: 91.07
• Hs Code.: 2928000090
• NSC Number: 136574
• DSSTox Substance ID: DTXSID20300392
• Wikidata: Q82043404
• ChEMBL ID: CHEMBL134941
• Mol file: 21520-79-6.mol

Synonyms:N-hydroxy-1-hydrazinecarboxamide;21520-79-6;N-hydroxyhydrazinecarboxamide;1-amino-3-hydroxyurea;hydroxyhydrazinecarboxamide;NSC136574;4-hydroxysemicarbazide;CHEMBL134941;DTXSID20300392;MFCD03791199;AKOS005070075;HYDRAZINECARBOXAMIDE,N-HYDROXY-;NSC-136574;SB86378;CS-0328319;FT-0680238;2W-0354;J-521473

Chemical Property of N-hydroxy-1-hydrazinecarboxamide

Chemical Property:

• Melting Point: 130-132 °C
• Refractive Index: 1.534
• Boiling Point: 358.6oC at 760mmHg
• Flash Point: 170.7oC
• PSA: 87.38000
• Density: 1.493 g/cm³
• LogP: 0.03060
• XLogP3: -1.3
• Hydrogen Bond Donor Count: 4
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 0
• Exact Mass: 91.038176411
• Heavy Atom Count: 6
• Complexity: 52.8

Purity/Quality:

97% ^*data from raw suppliers

N-Hydroxy-1-hydrazinecarboxamide ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C(=O)(NN)NO

Technology Process of N-hydroxy-1-hydrazinecarboxamide

There total 4 articles about N-hydroxy-1-hydrazinecarboxamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

phenyl N-hydroxycarbamate (38064-07-2) → 4-hydroxysemicarbazide (21520-79-6)

Guidance literature:

With hydrazine hydrate; In ethanol;

DOI:10.1021/jm010252q

Reference yield:

CH2NOS2(1-)*K(1+) → 4-hydroxysemicarbazide (21520-79-6)

Guidance literature:

With hydrazine hydrochloride; In ethanol; at 80 ℃; for 1h;

DOI:10.1016/j.bmcl.2007.01.037

Reference yield:

hydrazinecarboxylic acid methyl ester (6294-89-9) → 4-hydroxysemicarbazide (21520-79-6)

Guidance literature:

With sodium hydroxide; hydroxylamine hydrochloride; In water;

upstream raw materials:

hydrazinecarboxylic acid methyl ester

N-Hydroxy-carbamidsaeure-(2-hydroxyphenyl)-ester

phenyl N-hydroxycarbamate

Downstream raw materials:

C₈H₈N₄O₄

1-(4-acetamidobenzylidene)-4-hydroxysemicarbazide

C₈H₈ClN₃O₃