6294-89-9Relevant academic research and scientific papers
1,5-Di(nitramino)tetrazole: High Sensitivity and Superior Explosive Performance
Fischer, Dennis,Klap?tke, Thomas M.,Stierstorfer, J?rg
, p. 10299 - 10302 (2015)
Highly energetic 1,5-di(nitramino)tetrazole and its salts were synthesized. The neutral compound is very sensitive and one of the most powerful non-nuclear explosives to date. Selected nitrogen-rich and metal salts were prepared. The potassium salt can be used as a sensitizer in place of tetracene. The obtained compounds were characterized by low-temperature X-ray diffraction, IR and Raman spectroscopy, multinuclear NMR spectroscopy, elemental analysis, and DSC. Calculated energetic performances using the EXPLO5 code based on calculated (CBS-4M) heats of formation and X-ray densities support the high energetic performances of the 1,5-dinitraminotetrazolates as energetic materials. The sensitivities towards impact, friction, and electrostatic discharge were also explored.
Potassium 1,1′-dinitramino-5,5′-bistetrazolate: A primary explosive with fast detonation and high initiation power
Fischer, Dennis,Klapoetke, Thomas M.,Stierstorfer, Joerg
, p. 8172 - 8175 (2014)
Adequate primary explosives such as lead azide mostly contain toxic ingredients, which have to be replaced. A new candidate that shows high potential, potassium 1,1′-dinitramino-5,5′-bistetrazolate (K 2DNABT), was synthesized by a sophisticated synthetic procedure based on dimethylcarbonate and glyoxal. It was intensively characterized for its chemical (X-ray diffraction, EA, NMR and vibrational spectroscopy) and physico-chemical properties (sensitivity towards impact, friction, and electrostatic, DSC). The obtained primary explosive combines good thermal stability with the desired mechanical stability. Owing to its high heat of formation (326 kJ mol-1) and density (2.11 g cm-3), impressive values for its detonation velocity (8330 m s-1) and pressure (311 kbar) were computed. Its superior calculated performance output was successfully confirmed and demonstrated by different convenient energetic test methods.
Fluorescence and theoretical calculation of phenylhydrazone derivatives and fluorine boron complex: Synthesis and fluorescence characteristics
Tang, Ping,Lyu, Luping,Li, Yujin
, p. 10 - 16 (2020/02/13)
A sereis of phenylhydrazone-based derivatives and their corresponding BF2 complexes were synthesized efficiently by a three-step reaction. Photophysical performance was investigated in different organic solvents and in the solid state. Although these compounds exhibited feeble fluorescent intensity in solution-state, BF2 complexes showed weaker fluorescence in solid state compared to precursors 2, which were caused by slight geometry relaxation of upon photo excitation. Density Functional Theory calculations was carried out to confirm above inference.
A METHOD FOR PRODUCING POTASSIUM 1,1 -DINITRAMINO-5,5-BISTETRAZOLATE AND EXPLOSIVE COMPOSITIONS COMPRISING SAID SALT
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Paragraph 0051; 0065, (2020/06/16)
A method of producing K2DNABT wherein a biztetrazole intermediate is nitrated using a nitrating agent selected from the following: dinitronium disulphate; a mixture of nitric acid and sulfuric acid; a mixture of nitric acid and phosphorous pentoxide; and nitric acid with acetic anhydride.
Palladium-Catalyzed Oxidative C–H Alkoxycarbonylation of Arenes with Alkylcarbazates Directed by N-Heterocyclic Substituents
Yogesh Kumar, Gujjenahalli Ramalingaiah,Begum, Noor Shahina
supporting information, p. 4698 - 4704 (2020/07/04)
With alkyl carbazates as the green ester source, a novel palladium-catalyzed oxidative free radical carbonylative transformation of the C–H bond on aromatic rings to produce esters has been developed. Good yields of the corresponding products have been obtained with wide functional group tolerance and excellent regioselectivity. A variety of alkyl carbazates are found to be suitable reactants for the ortho-alkoxycarbonylation on the aromatic ring.
Phenylhydrazone fluorescent probe, preparation and applications thereof
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Paragraph 0039-0040, (2019/12/25)
The invention discloses a phenylhydrazone fluorescent probe, a preparation and applications thereof. According to the present invention, the fluorescence of the phenylhydrazone fluorescent probe can be enhanced in Al, Ba, Cu, Hg, Mg, Ag, Ni and Zn, can be even enhanced by more than 20 times in Mg and Ni, and is almost completely quenched in Fe, such thatthe results show that the complexed phenylhydrazone has good selectivity on iron metal ions, and can be used for the naked eye qualitative identification of iron ions.
An efficient protocol for the production of pymetrozine via a new synthetic strategy
Zhou, Qifan,Du, Fangyu,Shi, Yajie,Liu, Wenqiang,Liu, Dongdong,Chen, Guoliang
, p. 434 - 438 (2018/09/12)
A practical four-step synthesis of pymetrozine is reported, starting from a green chemical dimethyl carbonate and using the key intermediate methyl (E)-1-(2-oxopropyl)-2-(pyridin-3-ylmethylene)hydrazine-1-carboxylate. The main advantages of the route include inexpensive starting materials, environmental friendliness, short synthetic route, easy-to-use synthetic method and acceptable overall yield. A scale-up experiment was carried out to provide pymetrozine with 99.84% purity in 53.2% total yield.
Synthesis and biological activities of (E)-β-farnesene analogues containing 1,2,3-thiadiazole
Zhang, Jing-Peng,Qin, Yao-Guo,Dong, Ya-Wen,Song, Dun-Lun,Duan, Hong-Xia,Yang, Xin-Ling
supporting information, p. 372 - 376 (2017/01/25)
In order to discover novel compounds with high-activity to control aphid, a series of novel (E)-β-farnesene analogues containing 1,2,3-thiadiazole were designed and synthesized, and their structures were confirmed by IR,1H NMR,13C NMR, and HRMS (ESI). The stability of representative compounds was studied by HPLC and1H NMR techniques. Repellent activity results indicated that compounds 8h and 8j displayed 60.3% and 62.0% repellent rates, respectively. The aphicidal bioassay results showed that most analogues exhibited considerable aphicidal activity against Myzus persicae. Especially, analogues 8l, 8s and 8t exhibited high activity with LC50values of 33.4?μg/mL, 50.2?μg/mL and 61.8?μg/mL, respectively, which were higher than the lead compound (E)-β-farnesene, but lower than commercial insecticide pymetrozine with a LC50of 7.1?μg/mL.
Synthesis and biological evaluation of 4-methyl-1,2,3-thiadiazole-5-carboxaldehyde benzoyl hydrazone derivatives
Zhang, Jing-Peng,Li, Xiang-Yang,Dong, Ya-Wen,Qin, Yao-Guo,Li, Xin-Lu,Song, Bao-An,Yang, Xin-Ling
supporting information, p. 1238 - 1242 (2017/06/19)
To find new lead compounds with high biological activity, a series of novel 4-methyl-1,2,3-thiadiazole-5-carboxaldehyde benzoyl hydrazone derivatives were designed and synthesized. Their structures were confirmed by 1H NMR, 13C NMR, IR spectrum and elemental analysis. Preliminary bioassay indicated that the title compounds exhibited moderate to strong fungicidal activity against six fungi in vitro at 50?μg/mL. Moreover, some of the title compounds exhibited good curative activity against TMV in vivo at 500?μg/mL. The structure-activity relationship analysis of compounds against Valsa mali showed that compounds containing halogen at the para position on phenyl exhibited the best activity. Especially compound 8k showed broad spectrum fungicidal activities against Valsa mali, Botrytis cinerea, Pythium aphanidermatum, Rhizoctonia solani, Fusarium moniliforme and Alternaria solani with the EC50 values of 8.20, 24.42, 15.80, 40.53, 41.48, and 34.16?μg/mL, respectively.
A kind of naphthalimide derivatives, preparation method and application thereof
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Paragraph 0027; 0032-0034, (2017/12/06)
The invention discloses naphthalimide derivatives, a preparation method and applications thereof. The structure of the derivatives is represented by the formula (Y). In the formula (Y), the R represents a six-membered ring containing hetero-atoms, -NHCH2CH2OH, -NHCH2CH2N(CH3)2, or -NHCH2CH2CH2CH3, wherein the hetero-atoms are nitrogen atoms, oxygen atoms, or sulfur atoms, the six-membered ring containing hetero-atoms comprises at least one nitrogen atom, and the R is connected to the mother nucleus of a compound represented by the formula (T) through a nitrogen atom. The provided derivatives are prepared by grafting methyl carbazate to the active sites of naphthalimide. The derivatives can inhibit the growth of tumor cells from different tissues such as mammary glands, cervix, and the like, while normal human cells are barely influenced by the derivatives, and thus the derivatives have a wide prospect in preparation of drugs for inhibiting the growth of tumor cells.
