2'-Deoxy-2'-fluoro-5-iodocytidine

Base Information

Chemical Name:2'-Deoxy-2'-fluoro-5-iodocytidine
CAS No.:80791-93-1
Molecular Formula:C9H11FIN3O4
Molecular Weight:371.107
Hs Code.:
ChEMBL ID:CHEMBL2079653
DSSTox Substance ID:DTXSID10415000
Nikkaji Number:J1.342.600G
Wikidata:Q82224109
Mol file:80791-93-1.mol

Synonyms:80791-93-1;2'-DEOXY-2'-FLUORO-5-IODOCYTIDINE;2'-Deoxy-2'-fluoro-5-iodo-Cytidine;4-amino-1-[(2R,3R,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-iodo-1,2-dihydropyrimidin-2-one;4-amino-1-[(2R,3R,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-iodopyrimidin-2-one;SCHEMBL138935;CHEMBL2079653;DTXSID10415000;2-Deoxy-2-fluoro-5-iodocytidine;AKOS030528637;AG-H-25014;AS-61441;2(1H)-Pyrimidinone, 4-amino-1-(2-deoxy-2-fluoro-beta-D-ribofuranosyl)-5-iodo-;4-amino-1-((2R,3R,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-iodopyrimidin-2(1H)-one;4-amino-1-[(2R,3R,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]-5-iodo-pyrimidin-2-one

Suppliers and Price of 2'-Deoxy-2'-fluoro-5-iodocytidine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2''-Deoxy-2''-fluoro-5-iodocytidine
2.5mg
$ 45.00

Crysdot
2'-Deoxy-2'-fluoro-5-iodo-Cytidine 97%
1g
$ 1200.00

American Custom Chemicals Corporation
(2'R)-BETA-D-2'-DEOXY-2'-FLUORO-5-IODOCYTIDINE 95.00%
5MG
$ 505.05

Total 11 raw suppliers

Chemical Property of 2'-Deoxy-2'-fluoro-5-iodocytidine

Chemical Property:

PSA：110.60000
LogP:-0.40000
XLogP3:-0.7
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:2
Exact Mass:370.97783
Heavy Atom Count:18
Complexity:430

Purity/Quality:

99%, ^*data from raw suppliers

2''-Deoxy-2''-fluoro-5-iodocytidine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=C(C(=NC(=O)N1C2C(C(C(O2)CO)O)F)N)I
Isomeric SMILES:C1=C(C(=NC(=O)N1[C@H]2[C@@H]([C@@H]([C@H](O2)CO)O)F)N)I
Uses 2''-Deoxy-2''-fluoro-5-iodocytidine can be used in preparation of cytidine-5-carboxamide modified nucleotide and their incorporation into DNA.

Technology Process of 2'-Deoxy-2'-fluoro-5-iodocytidine

There total 4 articles about 2'-Deoxy-2'-fluoro-5-iodocytidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 67.0%

: 10212-20-1
2'-deoxy-2'-fluorocytidine

: 80791-93-1
5-iodo-2'-deoxy-2'-(R)-fluoro-cytidine

Guidance literature:: With iodine; 3-chloro-benzenecarboperoxoic acid; In N,N-dimethyl-formamide; at 20 ℃; for 7h;
DOI:10.1021/acs.orglett.6b02110