12-(2,5-Dimethoxy-3,4,6-trimethylphenyl)dodeca-2,7-diyn-1-OL

Base Information

Chemical Name:12-(2,5-Dimethoxy-3,4,6-trimethylphenyl)dodeca-2,7-diyn-1-OL
CAS No.:80810-05-5
Molecular Formula:C23H32O3
Molecular Weight:356.505
Hs Code.:
DSSTox Substance ID:DTXSID40607092
Nikkaji Number:J481.218B
Wikidata:Q82506035

Synonyms:80810-05-5;12-(2,5-DIMETHOXY-3,4,6-TRIMETHYLPHENYL)DODECA-2,7-DIYN-1-OL;SCHEMBL10891881;DTXSID40607092;TTYFPYCIZLFAHZ-UHFFFAOYSA-N;1-(12-hydroxydodeca-5,10-diynyl)-2,5-dimethoxy-3,4,6-trimethylbenzene

Suppliers and Price of 12-(2,5-Dimethoxy-3,4,6-trimethylphenyl)dodeca-2,7-diyn-1-OL

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of 12-(2,5-Dimethoxy-3,4,6-trimethylphenyl)dodeca-2,7-diyn-1-OL

Chemical Property:

XLogP3:5.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:8
Exact Mass:356.23514488
Heavy Atom Count:26
Complexity:515

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=C(C(=C(C(=C1OC)C)CCCCC#CCCCC#CCO)OC)C

Technology Process of 12-(2,5-Dimethoxy-3,4,6-trimethylphenyl)dodeca-2,7-diyn-1-OL

There total 11 articles about 12-(2,5-Dimethoxy-3,4,6-trimethylphenyl)dodeca-2,7-diyn-1-OL which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 80810-60-2
1,4-dimethoxy-2,3,5-trimethyl-6-(tetrahydrofur-2-yl)benzene

: 80810-05-5
1-(12-hydroxydodeca-5,10-diynyl)-2,5-dimethoxy-3,4,6-trimethylbenzene

Guidance literature:: Multi-step reaction with 9 steps

1: 90 percent / 70percent perchloric acid, hydrogen / 5percent palladium-charcoal / acetic acid / 1.5 h / 70 °C

2: triethylamine / CH₂Cl₂ / 1 h / -5 °C

3: sodium iodide / acetone / 2 h / 50 °C

4: 1.) sodium amide, 2.) hexamethylphosphoramide / 1.) THF, 50 deg C, 1.5 h, 2.) room temperature, 1 h

5: toluene-p-sulphonic acid / methanol / 0.5 h / 70 °C

6: triethylamine / CH₂Cl₂ / 1 h / -5 °C

7: sodium iodide / acetone / 2 h / 50 °C

8: 1.) sodium amide / 1.) Et₂O, liquid ammonia, -50 deg C - -40 deg C, 60 min, 2.) -50 deg C - -40 deg C, 100 min

9: toluene-p-sulphonic acid / methanol / 0.5 h / 70 °C

With N,N,N,N,N,N-hexamethylphosphoric triamide; perchloric acid; hydrogen; toluene-4-sulfonic acid; sodium amide; triethylamine; sodium iodide; palladium on activated charcoal; In methanol; dichloromethane; acetic acid; acetone;

Reference yield:

: 118647-24-8
2-[12-(2,5-Dimethoxy-3,4,6-trimethyl-phenyl)-dodeca-2,7-diynyloxy]-tetrahydro-pyran

: 80810-05-5
1-(12-hydroxydodeca-5,10-diynyl)-2,5-dimethoxy-3,4,6-trimethylbenzene

Guidance literature:: With toluene-4-sulfonic acid; In methanol; at 70 ℃; for 0.5h; Yield given;

Reference yield:

: 80810-61-3
4-(2,5-dimethoxy-3,4,6-trimethylphenyl)butan-1-ol

: 80810-05-5
1-(12-hydroxydodeca-5,10-diynyl)-2,5-dimethoxy-3,4,6-trimethylbenzene

Guidance literature:: Multi-step reaction with 8 steps

1: triethylamine / CH₂Cl₂ / 1 h / -5 °C

2: sodium iodide / acetone / 2 h / 50 °C

3: 1.) sodium amide, 2.) hexamethylphosphoramide / 1.) THF, 50 deg C, 1.5 h, 2.) room temperature, 1 h

4: toluene-p-sulphonic acid / methanol / 0.5 h / 70 °C

5: triethylamine / CH₂Cl₂ / 1 h / -5 °C

6: sodium iodide / acetone / 2 h / 50 °C

7: 1.) sodium amide / 1.) Et₂O, liquid ammonia, -50 deg C - -40 deg C, 60 min, 2.) -50 deg C - -40 deg C, 100 min

8: toluene-p-sulphonic acid / methanol / 0.5 h / 70 °C

With N,N,N,N,N,N-hexamethylphosphoric triamide; toluene-4-sulfonic acid; sodium amide; triethylamine; sodium iodide; In methanol; dichloromethane; acetone;