(25R)-Spirost-4-en-3-one

Base Information Edit

Chemical Name:(25R)-Spirost-4-en-3-one
CAS No.:6870-79-7
Molecular Formula:C27H40O3
Molecular Weight:412.613
Hs Code.:
Mol file:6870-79-7.mol

Synonyms:Diosgenon;(25R)-spirost-4-en-3-one;(25R)-Spirost-4-en-3-on;diosgenone;(25R)-4-spirosten-3-one;

Suppliers and Price of (25R)-Spirost-4-en-3-one

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 5 raw suppliers

Chemical Property of (25R)-Spirost-4-en-3-one Edit

Chemical Property:

PSA：35.53000
LogP:5.92210

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

General Description (25R)-Spirost-4-en-3-one, also known as diosgenone, is a steroidal compound derived from the natural sapogenin diosgenin. It serves as a key intermediate in microbial transformations and has potential therapeutic applications, such as in malaria treatment. Structurally, it features a spirostane skeleton with a 4-en-3-one moiety, and its (25R) configuration is significant in its biological activity. (25R)-Spirost-4-en-3-one can be synthesized via microbial oxidation pathways, involving 3β-hydroxyl oxidation and double bond isomerization, as demonstrated by the yeast strain *Wickerhamomyces anomalus* JQ-1. Its dynamic properties and interactions, including hydrogen bonding and packing effects, have been studied in the context of molecular rotors, highlighting its relevance in solid-state molecular machinery.

Technology Process of (25R)-Spirost-4-en-3-one

There total 13 articles about (25R)-Spirost-4-en-3-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 512-04-9
diosgenin

: 6870-79-7
(25R)-spirost-4-ene-3-one

Guidance literature:: With pyridinium chlorochromate; calcium carbonate; In dichloromethane; at 20 ℃; for 5h; Inert atmosphere;
DOI:10.1016/j.steroids.2020.108777