N-(2-hydroxy-5-methylphenyl)-4-methylbenzenesulfonamide

Base Information

Chemical Name:N-(2-hydroxy-5-methylphenyl)-4-methylbenzenesulfonamide
CAS No.:81256-11-3
Molecular Formula:C14H15NO3S
Molecular Weight:277.344
Hs Code.:
Mol file:81256-11-3.mol

Synonyms:N-Tosyl-4-methyl-2-aminophenol;N-(2-Hydroxy-5-methyl-phenyl)-4-methyl-benzenesulfonamide;N-(2-hydroxy-5-methylphenyl)-4-toluenesulfonamide;

Suppliers and Price of N-(2-hydroxy-5-methylphenyl)-4-methylbenzenesulfonamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of N-(2-hydroxy-5-methylphenyl)-4-methylbenzenesulfonamide

Chemical Property:

PSA：74.78000
LogP:3.96360

Purity/Quality:

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Technology Process of N-(2-hydroxy-5-methylphenyl)-4-methylbenzenesulfonamide

There total 9 articles about N-(2-hydroxy-5-methylphenyl)-4-methylbenzenesulfonamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

: C₂₁H₂₁NO₅S₂

: 81256-11-3
N-(2-hydroxy-5-methylphenyl)-4-methylbenzenesulfonamide

Guidance literature:: With magnesium; In methanol; at 40 ℃; for 12h;
DOI:10.1021/acs.orglett.8b00352

Reference yield: 85.0%

: 95-84-1
3-amino-4-hydroxytoluene

: 98-59-9
p-toluenesulfonyl chloride

: 81256-11-3
N-(2-hydroxy-5-methylphenyl)-4-methylbenzenesulfonamide

Guidance literature:: With pyridine; In dichloromethane; at 0 - 20 ℃;
DOI:10.1021/acs.orglett.1c02539

Reference yield: 72.0%

: 65109-76-4
N-p-toluenesulfonyl-O-(4-tolyl)-hydroxylamine

: 81256-11-3
N-(2-hydroxy-5-methylphenyl)-4-methylbenzenesulfonamide

Guidance literature:: With 1,1,1,3',3',3'-hexafluoro-propanol; at 60 ℃; for 24h; Reagent/catalyst; regioselective reaction;
DOI:10.1016/j.tetlet.2021.153601