65109-76-4

Basic information

• Product Name: Benzenesulfonamide, 4-methyl-N-(4-methylphenoxy)-
• CAS NO: 65109-76-4
• Molecular Formula: C14H15NO3S
• Molecular Weight: 277.344
• Mol File: 65109-76-4.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: Benzenesulfonamide, 4-methyl-N-(4-methylphenoxy)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenesulfonamide, 4-methyl-N-(4-methylphenoxy)-(65109-76-4)
• EPA Substance Registry System: Benzenesulfonamide, 4-methyl-N-(4-methylphenoxy)-(65109-76-4)

Safety Data

• Hazardous Substances Data: 65109-76-4(Hazardous Substances Data)

Upstream product

• 65440-81-5 O-(4-methylphenyl)hydroxylamine 
• 98-59-9 p-toluenesulfonyl chloride 
• 220464-86-8 N-(4-methylphenoxy)phthalimide 

Downstream Products

• 81256-11-3 N-(2-hydroxy-5-methylphenyl)-4-methylbenzenesulfonamide 
• 546-24-7 Pummerer ketone 
• 15519-73-0 2,2'-Dihydroxy-4,4'-dimethylbiphenyl 
• 89374-84-5 2-hydroxy-5-methylphenyl-p-toluenesulfonimidate 

Relevant articles and documents

Hexafluoroisopropanol (HFIP)-prompted rearrangement of N-phenoxysulfonamides for the direct assembly of ortho-sulfonamide phenols: A combined experimental and computational study

ortho-Sulfonamide phenols represent a class of attractive structural motifs in medicinal and synthetic chemistry. Herein an efficient metal-free rearrangement reaction has been developed for the construction of ortho-sulfonamide phenols via HFIP-prompted

Acid-Catalyzed Solvolysis of N-Sulfonyl- and N-Acyl-O-arylhydroxylamines. Phenoxenium Ions

The acid-catalyzed reaction of N-acyl- and N-sulfonyl-O-arylhydroxylamines with benzene proceeded quite smoothly to give 2- and 4-hydroxybiphenyls.The results of product analysis, the orientation of the reaction, and the effects of substituents on the nitrogen atom and on the phenyl ring suggested a mechanism that involves a phenoxenium ion.The phenoxenium ion was trapped by benzene and other various nucleophiles.