1-Methyl-2-oxo-N-phenyl-1,2-dihydropyridine-3-carboxamide

Base Information

Chemical Name:1-Methyl-2-oxo-N-phenyl-1,2-dihydropyridine-3-carboxamide
CAS No.:81685-52-1
Molecular Formula:C₁₃H₁₂N₂O₂
Molecular Weight:228.25
Hs Code.:
DSSTox Substance ID:DTXSID70510843
Wikidata:Q82369372

Synonyms:81685-52-1;1-Methyl-2-oxo-N-phenyl-1,2-dihydropyridine-3-carboxamide;DTXSID70510843;AKOS027598061

Suppliers and Price of 1-Methyl-2-oxo-N-phenyl-1,2-dihydropyridine-3-carboxamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 1 raw suppliers

Chemical Property of 1-Methyl-2-oxo-N-phenyl-1,2-dihydropyridine-3-carboxamide

Chemical Property:

XLogP3:1.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:228.089877630
Heavy Atom Count:17
Complexity:379

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CN1C=CC=C(C1=O)C(=O)NC2=CC=CC=C2

Technology Process of 1-Methyl-2-oxo-N-phenyl-1,2-dihydropyridine-3-carboxamide

There total 3 articles about 1-Methyl-2-oxo-N-phenyl-1,2-dihydropyridine-3-carboxamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

: 84854-00-2
1-Methyl-2-oxo-1,2-dihydro-pyridine-3-carbonyl chloride

: 62-53-3
aniline

: 81685-52-1
N-phenyl dihydro-1,2 methyl-1 oxo-2 pyridine-3 carboxamide

Guidance literature:: In benzene; for 0.166667h; Ambient temperature;

Reference yield:

: 15506-18-0
1-methyl-2-oxo-1,2-dihydropyridine-3-carboxylic acid

: 81685-52-1
N-phenyl dihydro-1,2 methyl-1 oxo-2 pyridine-3 carboxamide

Guidance literature:: Multi-step reaction with 2 steps

1: (COCl)2 / benzene / a) RT, 3 h, b) 50 - 55 deg C, 30 min

2: 70 percent / benzene / 0.17 h / Ambient temperature

With oxalyl dichloride; In benzene;

Reference yield:

: 1752-96-1
N-phenylnicotinamide

: 77-78-1
dimethyl sulfate

: 81685-52-1
N-phenyl dihydro-1,2 methyl-1 oxo-2 pyridine-3 carboxamide

: N-phenyl-1,2-dihydro-1-methyl-2-oxo-5-pyridinecarboxamide

Guidance literature:: With sodium hydroxide; potassium hexacyanoferrate(III); Yield given. Multistep reaction. Yields of byproduct given; 1.) dimethyl sulfoxide, heated on a boiling water bath, 4 h; 2) water, 10 deg C, 2 h;