Phosphorous acid, diphenyl 8-quinolinyl ester

Base Information

• Chemical Name: Phosphorous acid, diphenyl 8-quinolinyl ester
• CAS No.: 82204-63-5
• Molecular Formula: C21H16NO3P
• Molecular Weight: 361.337
• Mol file: 82204-63-5.mol

Synonyms:

Chemical Property of Phosphorous acid, diphenyl 8-quinolinyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Phosphorous acid, diphenyl 8-quinolinyl ester

There total 1 articles about Phosphorous acid, diphenyl 8-quinolinyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

8-quinolinol (148-24-3,24804-14-6) + Diphenyl phosphorochloridite (5382-00-3) → Phosphorous acid diphenyl ester quinolin-8-yl ester (82204-63-5)

Guidance literature:

With triethylamine; In benzene; at 0 ℃; for 0.5h;

Reference yield:

Phosphorous acid diphenyl ester quinolin-8-yl ester (82204-63-5) → 8-(4,4-Diphenoxy-4λ5-[1,2,3,4]trioxaphosphetan-4-yloxy)-quinoline

Guidance literature:

With ozone; In dichloromethane; at -70 ℃;

DOI:10.1016/S0040-4039(00)86848-3

Reference yield:

Phosphorous acid diphenyl ester quinolin-8-yl ester (82204-63-5) → phosphoric acid-[8]quinolyl ester-diphenyl ester (82204-51-1)

Guidance literature:

Multi-step reaction with 2 steps

1: ozone / dimethylformamide / -60 °C

2: CH2Cl2 / 32 °C / ΔG(excit); also at 44 deg C, DMF

With ozone; In dichloromethane; N,N-dimethyl-formamide;

upstream raw materials:

8-quinolinol

Diphenyl phosphorochloridite

Downstream raw materials:

phosphoric acid-[8]quinolyl ester-diphenyl ester