Technology Process of 9-Undecene-1,5-diol, 2,3,3-trimethoxy-6,8-dimethyl-7-(phenylsulfonyl)-
There total 14 articles about 9-Undecene-1,5-diol, 2,3,3-trimethoxy-6,8-dimethyl-7-(phenylsulfonyl)- which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 2 steps
1: 2.) MCPBA / 1.) THF, 0 deg C -> room temperature, 2.) CH2Cl2, 0 deg C, 0.5 h
2: 70 percent / NaBH4 / ethanol; tetrahydrofuran / 1 h / 80 °C
With
sodium tetrahydroborate; 3-chloro-benzenecarboperoxoic acid;
In
tetrahydrofuran; ethanol;
DOI:10.1021/ja00382a065
- Guidance literature:
-
Multi-step reaction with 13 steps
1: tetrahydrofuran; hexane / Ambient temperature
2: 92 percent / pyridine / CH2Cl2 / 0.5 h / 0 °C
4: MCPBA / CH2Cl2 / 72 h / Ambient temperature
5: 2. potassium fluoride / 1. -78 deg C/THF/5 min 2. MeOH/1 h/room temperature
6: 1. n-BuLi / 1. THF-HMPA, -78 deg C, 10 min 2. 0 deg C, 30 min
8: 92 percent / methyl orthoformate, d,l-camphersulphonic acid / 18 h / 80 °C
9: 5.6 g / CrO3*2Py / CH2Cl2 / 0.5 h / Ambient temperature
10: 94 percent / d,l-camphersulphonic acid / methanol / 12 h / Ambient temperature
11: 1. NaH / 1. 30 min/THF/0 deg C 2. THF/room temperature/12 h
12: 93 percent / MCPBA / CH2Cl2 / 0.5 h / 0 °C
13: 70 percent / NaBH4 / ethanol; tetrahydrofuran / 1 h / 80 °C
With
pyridine; potassium fluoride; sodium tetrahydroborate; n-butyllithium; 10-camphorsufonic acid; dipyridine chromium trioxide; sodium hydride; 3-chloro-benzenecarboperoxoic acid; trimethyl orthoformate;
In
tetrahydrofuran; methanol; ethanol; hexane; dichloromethane;
DOI:10.1021/jo00193a015
- Guidance literature:
-
Multi-step reaction with 13 steps
1: tetrahydrofuran; hexane / Ambient temperature
2: 92 percent / pyridine / CH2Cl2 / 0.5 h / 0 °C
4: MCPBA / CH2Cl2 / 72 h / Ambient temperature
5: 2. potassium fluoride / 1. -78 deg C/THF/5 min 2. MeOH/1 h/room temperature
6: 1. n-BuLi / 1. THF-HMPA, -78 deg C, 10 min 2. 0 deg C, 30 min
8: 92 percent / methyl orthoformate, d,l-camphersulphonic acid / 18 h / 80 °C
9: 5.6 g / CrO3*2Py / CH2Cl2 / 0.5 h / Ambient temperature
10: 94 percent / d,l-camphersulphonic acid / methanol / 12 h / Ambient temperature
11: 1. NaH / 1. 30 min/THF/0 deg C 2. THF/room temperature/12 h
12: 93 percent / MCPBA / CH2Cl2 / 0.5 h / 0 °C
13: 70 percent / NaBH4 / ethanol; tetrahydrofuran / 1 h / 80 °C
With
pyridine; potassium fluoride; sodium tetrahydroborate; n-butyllithium; 10-camphorsufonic acid; dipyridine chromium trioxide; sodium hydride; 3-chloro-benzenecarboperoxoic acid; trimethyl orthoformate;
In
tetrahydrofuran; methanol; ethanol; hexane; dichloromethane;
DOI:10.1021/jo00193a015
