2-Propyn-1-ol, 3-[dimethyl(phenylmethyl)silyl]-

Base Information

Chemical Name:2-Propyn-1-ol, 3-[dimethyl(phenylmethyl)silyl]-
CAS No.:82753-05-7
Molecular Formula:C12H16OSi
Molecular Weight:204.344
Hs Code.:
DSSTox Substance ID:DTXSID00464365

Synonyms:2-Propyn-1-ol, 3-[dimethyl(phenylmethyl)silyl]-;82753-05-7;DTXSID00464365

Suppliers and Price of 2-Propyn-1-ol, 3-[dimethyl(phenylmethyl)silyl]-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of 2-Propyn-1-ol, 3-[dimethyl(phenylmethyl)silyl]-

Chemical Property:

Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:3
Exact Mass:204.097041664
Heavy Atom Count:14
Complexity:227

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C[Si](C)(CC1=CC=CC=C1)C#CCO

Technology Process of 2-Propyn-1-ol, 3-[dimethyl(phenylmethyl)silyl]-

There total 4 articles about 2-Propyn-1-ol, 3-[dimethyl(phenylmethyl)silyl]- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 1833-31-4
benzyl(chloro)dimethylsilane

: 107-19-7
propargyl alcohol

: 82753-05-7
3-benzyldimethylsilylpropargyl alcohol

Guidance literature:: With n-butyllithium; In tetrahydrofuran;
DOI:10.1002/anie.201502086

Reference yield: 40.0%

: 1833-31-4
benzyl(chloro)dimethylsilane

: bis bromomagnesium salt of propargyl alcohol

: 82753-05-7
3-benzyldimethylsilylpropargyl alcohol

Guidance literature:: In tetrahydrofuran; for 6h; Heating;

Reference yield:

: 6089-04-9
3-(tetrahydropyran-2'-yloxy)propyne

: 1833-31-4
benzyl(chloro)dimethylsilane

: 82753-05-7
3-benzyldimethylsilylpropargyl alcohol

Guidance literature:: 3-(tetrahydropyran-2'-yloxy)propyne; With n-butyllithium; In tetrahydrofuran; at -78 ℃; for 1.5h; Inert atmosphere;

benzyl(chloro)dimethylsilane; In tetrahydrofuran; at -78 - 20 ℃; for 3.5h; Inert atmosphere;

With toluene-4-sulfonic acid; In methanol; at 20 ℃; for 2h; Inert atmosphere;
DOI:10.1016/j.tet.2018.04.021