(3Z,5S)-3-(1-Hydroxyethylidene)-5-[(S)-1-methylpropyl]-2,4-pyrrolidinedione

Base Information

Chemical Name:(3Z,5S)-3-(1-Hydroxyethylidene)-5-[(S)-1-methylpropyl]-2,4-pyrrolidinedione
CAS No.:75652-74-3
Molecular Formula:C₁₀H₁₅NO₃
Molecular Weight:197.234
Hs Code.:
Mol file:75652-74-3.mol

Synonyms:2,4-Pyrrolidinedione,3-(1-hydroxyethylidene)-5-(1-methylpropyl)-, [S-[R*,R*-(Z)]]-; L-Tenuazonicacid; Tenuazonic acid

Suppliers and Price of (3Z,5S)-3-(1-Hydroxyethylidene)-5-[(S)-1-methylpropyl]-2,4-pyrrolidinedione

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemicals and raw materials
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Total 7 raw suppliers

Chemical Property of (3Z,5S)-3-(1-Hydroxyethylidene)-5-[(S)-1-methylpropyl]-2,4-pyrrolidinedione

Chemical Property:

PSA：66.40000
LogP:1.26080

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of (3Z,5S)-3-(1-Hydroxyethylidene)-5-[(S)-1-methylpropyl]-2,4-pyrrolidinedione

There total 2 articles about (3Z,5S)-3-(1-Hydroxyethylidene)-5-[(S)-1-methylpropyl]-2,4-pyrrolidinedione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 55.0%

: 62972-98-9
(2S,3S)-N-acetoacetylisoleucine methyl ester

: 75652-74-3,99152-09-7,113757-63-4,120812-45-5,140837-95-2
(5RS)-3-<(Z)-1-hydroxyethylidene>-5-<(S)-1-methylpropyl>-2,4-pyrrolidinedione

Guidance literature:: With tetrabutyl ammonium fluoride; In tetrahydrofuran; for 24h; Heating;
DOI:10.1016/S0040-4020(01)88210-7

Reference yield:

: 2577-46-0
L-isoleucine methyl ester

: 75652-74-3,99152-09-7,113757-63-4,120812-45-5,140837-95-2
(5RS)-3-<(Z)-1-hydroxyethylidene>-5-<(S)-1-methylpropyl>-2,4-pyrrolidinedione

Guidance literature:: Multi-step reaction with 2 steps

1: 60 percent / silver(I) trifluoroacetate / tetrahydrofuran / 3 h / Ambient temperature

2: 55 percent / tetra-n-butylammonium fluoride / tetrahydrofuran / 24 h / Heating

With tetrabutyl ammonium fluoride; silver trifluoroacetate; In tetrahydrofuran;
DOI:10.1016/S0040-4020(01)88210-7