2-Bromo-6-phenoxypyridine

Base Information

• Chemical Name: 2-Bromo-6-phenoxypyridine
• CAS No.: 83247-00-1
• Molecular Formula: C11H8BrNO
• Molecular Weight: 250.095
• Hs Code.: 2933399090
• DSSTox Substance ID: DTXSID90356447
• Wikidata: Q82135781
• Mol file: 83247-00-1.mol

Synonyms:2-bromo-6-phenoxypyridine;83247-00-1;SCHEMBL4286;2-bromo-6-phenoxy-pyridine;DTXSID90356447;JCCHXHXBKRYZOA-UHFFFAOYSA-N;AMY27723;ZB1272;AKOS013278721;2-Bromo-6-phenoxypyridine, AldrichCPR;AB09566;AS-58387;CS-0235926;D93580;EN300-1653595;A904897;AC-907/30063030;J-508491

Chemical Property of 2-Bromo-6-phenoxypyridine

Chemical Property:

• Melting Point: 83-86 °C
• Boiling Point: 327.2±27.0 °C(Predicted)
• PKA: -1.90±0.12(Predicted)
• PSA: 22.12000
• Density: 1.476±0.06 g/cm3(Predicted)
• LogP: 3.63640
• Storage Temp.: 2-8°C
• XLogP3: 3.7
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 2
• Exact Mass: 248.97893
• Heavy Atom Count: 14
• Complexity: 171

Purity/Quality:

97% ^*data from raw suppliers

2-Bromo-6-phenoxypyridine 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C=C1)OC2=NC(=CC=C2)Br

Technology Process of 2-Bromo-6-phenoxypyridine

There total 3 articles about 2-Bromo-6-phenoxypyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

2,6-Dibromopyridine (626-05-1) + phenol (108-95-2,27073-41-2) → 2-bromo-6-phenoxypyridine (83247-00-1)

Guidance literature:

With potassium tert-butylate; In dimethyl sulfoxide; at 160 ℃; for 7h;

Reference yield:

2,6-Dibromopyridine (626-05-1) + sodium phenoxide (139-02-6) → 2-bromo-6-phenoxypyridine (83247-00-1)

Guidance literature:

With water; at 150 ℃; unter Druck_.;

Reference yield:

2,6-Dibromopyridine (626-05-1) → 2-bromo-6-phenoxypyridine (83247-00-1)

Guidance literature:

at 150 ℃;

upstream raw materials:

2,6-Dibromopyridine

sodium phenoxide

phenol

Downstream raw materials:

2-phenoxypyridine

6-phenoxy-pyridin-2-ylcarboxaldehyde

1-(6-phenoxy-2-pyridinyl)-2,2,2-trifluoroethanone

6-phenoxypicolinonitrile