N,N-Dipropyl-6,7,8,9-tetrahydro-3H-benzo[e]indol-8-amine

Base Information

Chemical Name:N,N-Dipropyl-6,7,8,9-tetrahydro-3H-benzo[e]indol-8-amine
CAS No.:83343-44-6
Molecular Formula:C18H26N2
Molecular Weight:270.418
Hs Code.:
ChEMBL ID:CHEMBL65196
DSSTox Substance ID:DTXSID10518060
Nikkaji Number:J622.387G
Pharos Ligand ID:CTCKY9VN4ZW4,CTCRPUBDTQFZ

Synonyms:CHEMBL65196;83343-44-6;N,N-Dipropyl-6,7,8,9-tetrahydro-3H-benzo[e]indol-8-amine;SCHEMBL8315482;DTXSID10518060;BDBM50035329;L005582;Dipropyl-(6,7,8,9-tetrahydro-3H-benzo[e]indol-8-yl)-amine;(+/-)-Dipropyl-(6,7,8,9-tetrahydro-3H-benzo[e]indol-8-yl)-amine

Suppliers and Price of N,N-Dipropyl-6,7,8,9-tetrahydro-3H-benzo[e]indol-8-amine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of N,N-Dipropyl-6,7,8,9-tetrahydro-3H-benzo[e]indol-8-amine

Chemical Property:

XLogP3:4.6
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:5
Exact Mass:270.209598838
Heavy Atom Count:20
Complexity:298

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCCN(CCC)C1CCC2=C(C1)C3=C(C=C2)NC=C3

Technology Process of N,N-Dipropyl-6,7,8,9-tetrahydro-3H-benzo[e]indol-8-amine

There total 1 articles about N,N-Dipropyl-6,7,8,9-tetrahydro-3H-benzo[e]indol-8-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 51512-09-5
2-(2-chlorophenyl)acetyl chloride

: 83343-44-6
6,7,8,9-tetrahydro-N,N-dipropyl-3H-benz[e]indol-8-amine

Guidance literature:: Multi-step reaction with 8 steps

1: AlCl₃ / CH₂Cl₂ / 2 h / -5 - 25 °C

2: 1.) NaCNBH₄, 2.) aq. HCl / 1.) MeOH, RT, 15 h

3: Et₃N / CH₂Cl₂ / 0.17 h / Ambient temperature

4: 41 percent / HN₀₃, H₂SO₄ / nitromethane / 1 h / -5 °C

5: NH₄COOH / Pd/C / methanol / Ambient temperature

6: LiAlH₄ / diethyl ether / 15 h / Ambient temperature

7: NH₂OH*HCl, Na₂SO₄ / H₂O / 1 h / Heating

8: 1.) 90 percent aq. H₂SO₄, 2.) LiAlH₄ / 1.) a) RT, 0.5 h, b) 80 deg C, 0.5 h, 2.) diethyl ether, RT, 1 h

With hydrogenchloride; lithium aluminium tetrahydride; aluminium trichloride; sulfuric acid; hydroxylamine hydrochloride; nitric acid; ammonium formate; sodium cyanoborohydride; sodium sulfate; triethylamine; palladium on activated charcoal; In methanol; diethyl ether; nitromethane; dichloromethane; water;
DOI:10.1021/jm00067a002