2-Chlorophenylacetyl chloride

Base Information

• Chemical Name: 2-Chlorophenylacetyl chloride
• CAS No.: 51512-09-5
• Molecular Formula: C8H6Cl2O
• Molecular Weight: 189.041
• Hs Code.: 29163990
• Mol file: 51512-09-5.mol

Synonyms:2-Chlorophenylacetyl chloride;o-Chlorophenylacetylchloride;2-Chlorophenylacetyl chloride,97%;

Chemical Property of 2-Chlorophenylacetyl chloride

Chemical Property:

• Vapor Pressure: 0.017mmHg at 25°C
• Refractive Index: 1.551
• Boiling Point: 254.7 °C at 760 mmHg
• Flash Point: 103 °C
• PSA: 17.07000
• Density: 1.324 g/cm³
• LogP: 2.64790
• Storage Temp.: 0-10°C

Purity/Quality:

97% ^*data from raw suppliers

2-Chlorophenylacetyl Chloride ^*data from reagent suppliers

Safty Information:

• Statements: 22-29-34
• Safety Statements: 26-36/37/39-45

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-Chlorophenylacetyl chloride

There total 8 articles about 2-Chlorophenylacetyl chloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

2'-chloro-benzeneacetic acid (2444-36-2) → 2-(2-chlorophenyl)acetyl chloride (51512-09-5)

Guidance literature:

With thionyl chloride; N,N-dimethyl-formamide; In toluene;

DOI:10.1021/jm00363a001

Reference yield:

2'-chloro-benzeneacetic acid (2444-36-2) → 8-chloro-3,4-dihydro-2(1H)-naphthalenone (82302-27-0) + 2-(2-chlorophenyl)acetyl chloride (51512-09-5)

Guidance literature:

With thionyl chloride;

Reference yield:

2'-chloro-benzeneacetic acid (2444-36-2) + oxalyl dichloride (79-37-8) → 2-(2-chlorophenyl)acetyl chloride (51512-09-5)

Guidance literature:

In dichloromethane; N,N-dimethyl-formamide;

upstream raw materials:

2'-chloro-benzeneacetic acid

1-(2-chlorophenyl)-2-diazoethan-1-one

o-chlorobenzoyl chloride

ortho-chlorobenzoic acid

Downstream raw materials:

(2-chloro-phenyl)-acetic acid-(4-dimethylamino-anilide)

(2-chloro-phenyl)-[2]pyridyl-acetic acid dimethylamide

2'-chloro-2,4-dimethyl-deoxybenzoin

1-phenyl-2-(2-chlorophenyl)ethanone

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